[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605701":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":12,"responsibleParty":35,"collaborators":10,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":10,"eligibilityCriteria":43,"healthyVolunteers":40,"sex":44,"minAge":10,"maxAge":10,"enrollmentInfo":45,"targetDuration":10,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":10,"overallStatus":14,"whyStopped":10,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Neonatal Encephalopathy",null,"Individuals with a history of NE who are less than 6 years old at the time of enrollment and available biological parents. Must be followed clinically at Boston Children's Hospital. Research genomic sequencing with CLIA confirmation of diagnostic findings. Those with an existing genetic diagnosis or who are deceased prior to enrollment are ineligible.",[13],{"facility":5,"status":14,"city":15,"state":16,"zip":17,"country":18,"countryCode":19,"cosmosGeoPoint":20,"geoPoint":25,"contacts":26},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":21,"coordinates":22},"Point",[23,24],-71.05977,42.35843,{"lat":24,"lon":23},[27,32],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"D'Gama Lab","CONTACT","617-355-5254","dgamalab@childrens.harvard.edu",{"name":33,"role":34,"phone":10,"phoneExt":10,"email":10},"Alissa D'Gama, MD, PhD","PRINCIPAL_INVESTIGATOR",{"type":34,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Alissa D'Gama","Assistant Professor of Pediatrics","100605701","genetics-of-neonatal-encephalopathy-and-related-disorders-100605701",false,"NCT07165938","Genetics of Neonatal Encephalopathy and Related Disorders","Proband Criteria:\n\nInclusion Criteria:\n\n* Diagnosed with neonatal encephalopathy during the neonatal period as documented in the electronic medical record\n* Less than 6 years old at the time of study enrollment\n* Patient at Boston Children's Hospital\n\nExclusion Criteria:\n\n* Genetic cause of NE already identified\n* Deceased prior to enrollment\n\nParent criteria:\n\nInclusion Criteria:\n\n\\- Biological parent of eligible proband (see above)","ALL",{"count":46,"type":47},300,"ESTIMATED","OBSERVATIONAL","Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to neonatal encephalopathy (NE) and related disorders. These findings may help explain the broad spectrum of clinical features and outcomes seen in individuals with a history of NE.",[9,51],"Hypoxic Ischaemic Encephalopathy (HIE)","2026-03-09",{"date":54,"type":55},"2026-03-11","ACTUAL",{"date":57,"type":55},"2026-02-04",{"date":59,"type":47},"2035-09",{"name":5,"class":6},1]