[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628305":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":16,"locations":24,"responsibleParty":47,"collaborators":7,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":7,"enrollmentInfo":59,"targetDuration":7,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":27,"whyStopped":7,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Medical University of Graz","OTHER",null,[9,12,14],{"name":10,"affiliation":5,"role":11},"Christina Stern, Dr. med.","PRINCIPAL_INVESTIGATOR",{"name":13,"affiliation":5,"role":11},"Ursula Hiden, PhD",{"name":15,"affiliation":5,"role":11},"Evelyn Jantscher-Krenn, PhD",[17,21],{"name":15,"role":18,"phone":19,"phoneExt":7,"email":20},"CONTACT","+43 316 385 80076","evelyn.jantscher-krenn@medunigraz.at",{"name":10,"role":18,"phone":22,"phoneExt":7,"email":23},"+43 316 385 86306","christina.stern@medunigraz.at",[25],{"facility":26,"status":27,"city":28,"state":7,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Department of Obstetrics and Gynecology, Medical University of Graz","RECRUITING","Graz","8036","Austria","AT",{"type":33,"coordinates":34},"Point",[35,36],15.44197,47.06733,{"lat":36,"lon":35},[39,40,41,42,43,44],{"name":15,"role":18,"phone":19,"phoneExt":7,"email":20},{"name":10,"role":18,"phone":7,"phoneExt":7,"email":23},{"name":10,"role":11,"phone":7,"phoneExt":7,"email":7},{"name":15,"role":11,"phone":7,"phoneExt":7,"email":7},{"name":13,"role":11,"phone":7,"phoneExt":7,"email":7},{"name":45,"role":46,"phone":7,"phoneExt":7,"email":7},"Federica Piani, DM, PhD","SUB_INVESTIGATOR",{"type":48,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100628305","gestational-diabetes-and-health-outcomes-in-mothers-and-babies-100628305",false,"NCT07459907","Gestational Diabetes and Health Outcomes in Mothers and Babies","Understanding the Effects of Gestational Diabetes on Mother and Baby","GRAZ-GDM","Inclusion Criteria:\n\n* ongoing pregnancy prior to the 32nd gestational week and a positive GDM screening\n\nExclusion Criteria:\n\n* gestational age 32nd gestational week\n* fetal genetic anomalies \u002Fmalformation","FEMALE","18 Years",{"count":60,"type":61},400,"ESTIMATED","OBSERVATIONAL","Gestational diabetes mellitus (GDM) is a common pregnancy complication characterized by impaired glucose metabolism and increased insulin resistance. GDM is associated with adverse pregnancy outcomes and an increased long-term risk of metabolic and cardiovascular disease for both mother and offspring.\n\nThis prospective observational cohort study aims to establish a longitudinal pregnancy and birth cohort of women diagnosed with GDM. Pregnant women with a positive 75 g oral glucose tolerance test (OGTT) between gestational weeks 24 and 28 will be recruited after diagnosis and followed through late pregnancy, delivery, and early postpartum.\n\nParticipants will undergo two study visits during pregnancy, sample collection at delivery, and one postpartum visit 8-12 weeks after birth. Clinical data, physical measurements, questionnaire-based information, and biological samples will be collected from mothers and infants to enable comprehensive phenotyping of GDM pregnancies.\n\nData and biosamples from this cohort will be used for descriptive and hypothesis-driven analyses and may be compared with data from an existing longitudinal cohort of healthy pregnancies to support interpretation of GDM-related changes.",[65,66],"Gestational Diabetes Mellitus (GDM)","Pregnancy",[68,69,70,71,72,73,74,66,75,76,77,78],"GDM","Insulin resistance","Glucose metabolism","Cardiometabolic risk","Pregnancy outcomes","Pregnancy phenotyping","Maternal and infant health","Post-partum follow up","Longitudinal cohort","Fetal growth","Neonatal adiposity","2026-04-09",{"date":81,"type":82},"2026-04-13","ACTUAL",{"date":84,"type":82},"2025-06-15",{"date":86,"type":61},"2035-06",{"name":5,"class":6},1]