[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100221816":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":33,"locations":41,"responsibleParty":76,"collaborators":10,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":10,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":93,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Indiana University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"GI Neuromuscal Disorder Cohort",null,"Patients who are undergoing surgical full-thickness biopsy of the stomach and\u002For proximal jejunum for the clinical evaluation of GI neuromuscular disorder",[13],"Procedure: Surgical Full Thickness Biopsy",{"label":15,"type":10,"description":16,"interventionNames":17},"GI Surgery Patients without neuromuscal disorders (control) cohort","Patients undergoing esophagectomy, sleeve gastrectomy for obesity, Roux-en-Y gastric bypass, whipple surgery, transplant surgery, or organ donors.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Surgical Full Thickness Biopsy","Eligible subjects will undergo a surgical full thickness biopsy of the stomach and\u002For proximal jejunum as part of their planned surgery.",[9,15],[25,26,27,28],"Biopsy","Surgical","Full-thickness","Stomach",[30],{"name":31,"affiliation":5,"role":32},"John M Wo, MD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":35,"role":36,"phone":10,"phoneExt":10,"email":37},"Maureen M Schilling, MD","CONTACT","maschi@iu.edu",{"name":39,"role":36,"phone":10,"phoneExt":10,"email":40},"John Wo","jmwo@iu.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Indiana University Hosptial","RECRUITING","Indianapolis","Indiana","46202","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-86.15804,39.76838,{"lat":54,"lon":53},[57,59,62,65,67,69,71,73,75],{"name":39,"role":36,"phone":10,"phoneExt":10,"email":58},"jwo@iu.edu",{"name":60,"role":36,"phone":61,"phoneExt":10,"email":37},"Maureen Schilling","3172782064",{"name":63,"role":64,"phone":10,"phoneExt":10,"email":10},"Tom V Nowak, MD","SUB_INVESTIGATOR",{"name":66,"role":64,"phone":10,"phoneExt":10,"email":10},"Attila Nakeeb, MD",{"name":68,"role":64,"phone":10,"phoneExt":10,"email":10},"Paul Herring, PhD",{"name":70,"role":64,"phone":10,"phoneExt":10,"email":10},"Muhammad T Idress",{"name":72,"role":64,"phone":10,"phoneExt":10,"email":10},"Chandrashekhar A Kubal, MD",{"name":74,"role":64,"phone":10,"phoneExt":10,"email":10},"Jennifer Choi, MD",{"name":31,"role":32,"phone":10,"phoneExt":10,"email":10},{"type":32,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"John M. Wo","MD","100221816","gi-neuromuscular-pathology-prospective-registry-100221816",false,"NCT02165059","GI Neuromuscular Pathology Prospective Registry","Indiana University GI Neuromuscular Pathology Prospective Registry","Inclusion Criteria Study Group:\n\nPatients who are undergoing surgical full-thickness biopsy of the stomach and\u002For proximal jejunum for the clinical evaluation of GI neuromuscular disorder.\n\nInclusion Criteria Control Group:\n\nPatients undergoing esophagectomy, sleeve gastrectomy for obesity, or Roux-en Y gastric bypass Patients undergoing Whipple surgery Patients undergoing transplant surgery\n\nPatients who are organ donors and undergoing surgery\n\nExclusion Criteria Study Group:\n\nContraindication for surgical full-thickness biopsy for any reason. Significant comorbidity due to severe cardiovascular, renal, pulmonary, or liver disease.\n\nSignificant coagulopathy Non-ambulatory patients: bed-ridden, nursing home resident. Pregnant Unable to give own informed consent Prisoners\n\nExclusion Criteria Control Group:\n\nPrior diagnosis of gastroparesis Prior diagnosis of chronic intestinal pseudo-obstruction Unable to give own informed consent if not an organ donor",true,"ALL","6 Months","90 Years",{"count":91,"type":92},300,"ESTIMATED","2 Years","OBSERVATIONAL","In this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future prognosis and predict response to gastric electrical stimulation (GES).",[97],"Gastroparesis",[99,100,101,102,103,104],"Nausea","Vomiting","Functional dyspepsia","Bloating","Regurgitation","Retching","2026-06-15",{"date":107,"type":108},"2026-06-16","ACTUAL",{"date":110,"type":108},"2013-12-01",{"date":112,"type":92},"2026-12",{"name":5,"class":6},1]