[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526016":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":36,"centralContacts":44,"locations":50,"responsibleParty":144,"collaborators":146,"id":154,"slug":155,"hasResults":156,"nctId":157,"briefTitle":158,"officialTitle":158,"acronym":159,"eligibilityCriteria":160,"healthyVolunteers":161,"sex":162,"minAge":163,"maxAge":164,"enrollmentInfo":165,"targetDuration":10,"studyType":168,"phases":10,"briefSummary":169,"conditions":170,"keywords":172,"overallStatus":66,"whyStopped":10,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":185},{"fullName":5,"class":6},"International Vaccine Institute","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Cross-Sectional Survey",null,"There are total 14 CSS groups among 8 participating countries: Bangladesh has 3 groups for CSS (urban CSS, rural CSS, displaced population CSS); Pakistan has 3 groups for CSS (urban CSS, rural CSS, commercial sex worker population CSS); Nepal has 1 nationally representative CSS; Sierra Leon has 1 rural CSS; Tanzania has 2 groups for CSS (pastoralists CSS, displaced population CSS); Ghana has 1 urban CSS; Zambia has 1 group for urban \\& rural representative CSS; DR Congo has 2 groups for CSS (population representative sample for urban and rural CSS, displaced population CSS)",[13],"Other: Urine Sample Collection",{"label":15,"type":10,"description":16,"interventionNames":17},"Longitudinal Study","There are total 11 LS groups: Bangladesh has 2 LS groups (married women up to 25 years-old \\& 26-35 years old); Sierra Leone has 2 LS groups (Young girls subject to child marriage\u002Fearly pregnancy \\& general population); Tanzania has 2 LS groups (fishing, mining\u002Ftuck stop community \\& general population) Other 5 countries have 1 LS group in each country.",[13,18,19],"Other: Self-collected Vaginal Swab","Other: Blood Samples",{"label":21,"type":10,"description":22,"interventionNames":10},"Qualitative Study","The qualitative sub-studies in five selected countries (Bangladesh, Nepal, Pakistan, Sierra Leone, DR Congo) will follow and draw on findings from the CSS, focusing on girls and women of different age strata as well as community members (including boys and men) and key informants in the health care system in each study site. Qualitative study methods will vary depending on the site and CSS findings, but will include both individual in- depth interviews (IDIs) (up to \\~ 30 individuals per site), key informant interviews as well as multiple focus group discussions (FGDs) with \\~6-8 participants\u002Fgroup. Detailed qualitative study methodology will be developed separately as another study protocol and adapted according to the procedures for each site.",[24,28,32],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Urine Sample Collection","When urine is collected as a sample in either CSS or LS, first flow urine samples will be collected",[9,15],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"Self-collected Vaginal Swab","Self-collected Vaginal Swab will be collected by the participant under the supervision of a trained nurse or other health care worker.",[15],{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"Blood Samples","If funding permits, a blood sample may be collected from participants in LS once during the follow-up period. If blood sample collection was not feasible during a visit, two additional attempts may be made to collect blood samples from LS participants during the subsequent follow-up visits.",[15],[37,41],{"name":38,"affiliation":39,"role":40},"Alexandra Hill","Associate Research Scientist","PRINCIPAL_INVESTIGATOR",{"name":42,"affiliation":43,"role":40},"Deborah Watson-Jones","Professor of Clinical Epidemiology & International Health",[45],{"name":46,"role":47,"phone":48,"phoneExt":10,"email":49},"Julia Lynch","CONTACT","+8228811149","julia.lynch@ivi.int",[51,64,81,92,103,114,124,134],{"facility":52,"status":53,"city":54,"state":10,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":10},"Diarrhoeal Disease Research, Bangladesh (icddr,b)","COMPLETED","Dhaka","1212","Bangladesh","BD",{"type":59,"coordinates":60},"Point",[61,62],90.40744,23.7104,{"lat":62,"lon":61},{"facility":65,"status":66,"city":67,"state":10,"zip":10,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Institut National pour la Recherche Biomedicale (INRB)","RECRUITING","Kinshasa","Democratic Republic of the Congo","CD",{"type":59,"coordinates":71},[72,73],15.31357,-4.32758,{"lat":73,"lon":72},[76,80],{"name":77,"role":47,"phone":78,"phoneExt":10,"email":79},"Hugo Kavunga","+243823875153","hugokavunga@gmail.com",{"name":77,"role":40,"phone":10,"phoneExt":10,"email":10},{"facility":82,"status":53,"city":83,"state":84,"zip":10,"country":85,"countryCode":86,"cosmosGeoPoint":87,"geoPoint":91,"contacts":10},"University of Health and Allied Sciences (UHAS)","Ho","Volta Region","Ghana","GH",{"type":59,"coordinates":88},[89,90],0.4713,6.60084,{"lat":90,"lon":89},{"facility":93,"status":53,"city":94,"state":10,"zip":95,"country":96,"countryCode":97,"cosmosGeoPoint":98,"geoPoint":102,"contacts":10},"Dhulikhel Hospital Kathmandu University Hospital (DHKUH)","Dhulikhel","45200","Nepal","NP",{"type":59,"coordinates":99},[100,101],85.54281,27.6221,{"lat":101,"lon":100},{"facility":104,"status":53,"city":105,"state":10,"zip":106,"country":107,"countryCode":108,"cosmosGeoPoint":109,"geoPoint":113,"contacts":10},"Aga Khan University (AKU)","Karachi","74800","Pakistan","PK",{"type":59,"coordinates":110},[111,112],67.0104,24.8608,{"lat":112,"lon":111},{"facility":115,"status":53,"city":116,"state":10,"zip":10,"country":117,"countryCode":118,"cosmosGeoPoint":119,"geoPoint":123,"contacts":10},"College of Medicine and Allied Health Sciences (COMAHS)","Freetown","Sierra Leone","SL",{"type":59,"coordinates":120},[121,122],-13.2356,8.48714,{"lat":122,"lon":121},{"facility":125,"status":53,"city":126,"state":10,"zip":127,"country":128,"countryCode":10,"cosmosGeoPoint":129,"geoPoint":133,"contacts":10},"Mwanza Intervention Trial Unit (MITU)","Mwanza","11936","Tanzania",{"type":59,"coordinates":130},[131,132],32.9,-2.51667,{"lat":132,"lon":131},{"facility":135,"status":53,"city":136,"state":10,"zip":10,"country":137,"countryCode":138,"cosmosGeoPoint":139,"geoPoint":143,"contacts":10},"ZAMBART","Lusaka","Zambia","ZM",{"type":59,"coordinates":140},[141,142],28.28713,-15.40669,{"lat":142,"lon":141},{"type":145,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[147,149,151],{"name":148,"class":6},"London School of Hygiene and Tropical Medicine",{"name":150,"class":6},"Karolinska Institutet",{"name":152,"class":153},"Centers for Disease Control and Prevention","FED","100526016","global-burden-estimation-of-human-papillomavirus-globe-hpv-100526016",false,"NCT06129253","Global Burden Estimation of Human Papillomavirus (GLOBE-HPV)","HPV","Inclusion Criteria:\n\n1. 9 to 50 years old (for urban and rural CSSs) at the time of enrollment.\n2. Resident in the selected community for at least the past 3 months (with the exception of pastoralists, refugees, and commercial sex workers).\n3. Able to understand the purpose of the study and study procedures.\n4. If aged 18 years or older or legally considered an emancipated minor, able and willing to provide consent to participate in the study including sample collection.\n5. If aged \\\u003C18 years (and not considered an emancipated minor), supported in their participation by a parent or guardian who is able and willing to provide consent, and\n6. If aged \\\u003C18 years (and not considered an emancipated minor), able and willing to provide assent to participate in the study.\n\nExclusion Criteria:\n\n1. Decline consent to participate any activity of the study.\n2. A medical condition or other reason, not directly related to HPV infection or HPV-related diseases, in the opinion of the investigator, precludes enrolment in the study.",true,"FEMALE","9 Years","50 Years",{"count":166,"type":167},29750,"ESTIMATED","OBSERVATIONAL","This study is a multi-country and multi-site project to estimate the point-prevalence of high-risk (HR) HPV genotype infections among representative samples of girls and women aged 9-50 years, and among specific sub-populations to estimate the incidence of persistent HPV infection among sexually active young women. The data to fulfill the objectives will be collected through a series of Cross-Sectional Surveys (CSS) and Longitudinal Studies (LS) in all 8 countries 3 South Asian countries including Bangladesh, Pakistan, Nepal and 5 sub-Saharan African countries including Sierra Leone, Tanzania, Ghana, Zambia and DR Congo. Qualitative sub-studies (QS) will be conducted in selected countries and populations following the CSS to further understand and unpack risk factors for HPV infection as well as to explore how gender-related dynamics including perceptions of gender norms and stigma, influence HPV burden and\u002For create barriers that shape girls\u002Fwomen access to and uptake of HPV prevention, screening, and treatment services. Specific study protocols and corresponding ethical applications for the qualitative sub-studies will be developed separately.",[171],"HPV Infection",[173,171,174,175],"HPV Positivity","High Risk (HR) HPV","Cervical Cancer","2025-07-15",{"date":178,"type":179},"2025-07-16","ACTUAL",{"date":181,"type":179},"2023-11-23",{"date":183,"type":167},"2027-12",{"name":5,"class":6},8]