[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630262":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":22,"responsibleParty":38,"collaborators":40,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Korea University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Community-Dwelling Older Adults in Seoul",null,"Community-dwelling older adults aged 60 and older recruited from the Seongbuk Senior Welfare Center in Seoul, Republic of Korea.\n\nInclusion criteria: Adults aged 60 or older residing in Korea; Samsung Galaxy smartphone users; MMSE score of 21 or above; those not meeting cognitive criteria may participate with legal guardian consent.\n\nExclusion criteria: Dementia diagnosis at baseline; severe visual or hearing impairments; illiteracy; less than 80% compliance with 2-day preliminary EMA protocol; alcohol or substance abuse; inability to ambulate or psychiatric conditions preventing participation; current cancer treatment or chemotherapy within past 6 months.\n\nThis is a prospective observational cohort. Participants complete baseline assessments, then a two-week EMA period using a smartphone app for daily emotions, cognition, and social interactions. Galaxy Watch monitors sleep, heart rate, and activity. Blood samples collected for inflammatory biomarkers. Follow-ups at 6 and 12 months.",[13],{"name":14,"affiliation":5,"role":15},"Sunmi Song","PRINCIPAL_INVESTIGATOR",[17],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Sunmi Song, PhD","CONTACT","+82232904439","sunmi.song0715@gmail.com",[23],{"facility":5,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":10,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Seoul","Select One...","02841","South Korea",{"type":30,"coordinates":31},"Point",[32,33],126.9784,37.566,{"lat":33,"lon":32},[36],{"name":14,"role":19,"phone":37,"phoneExt":10,"email":21},"01087489593",{"type":15,"investigatorFullName":14,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Research Professor",[41,43,45],{"name":42,"class":6},"Korea University Anam Hospital",{"name":44,"class":6},"Penn State University",{"name":46,"class":6},"Albert Einstein College of Medicine","100630262","global-collaborative-research-on-establishing-a-korean-cognitive-aging-cohort-100630262",false,"NCT07485387","Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort","Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort That is Associated With the Einstein Aging Study","KoCoA cohort","Inclusion Criteria:\n\n* Adults aged 60 or older residing in the Republic of Korea\n* Samsung Galaxy smartphone users capable of using smartphone applications\n* Sufficient cognitive ability to understand and follow research instructions (MMSE score of 21 or above)\n* For individuals who do not meet the cognitive criteria, those who understand the study procedures and provide informed consent along with their legal guardian\n\nExclusion Criteria:\n\n* Diagnosis of dementia at baseline\n* Severe visual or hearing impairments that prevent participation in psychological assessments\n* Illiteracy that prevents participation in cognitive testing\n* Less than 80% compliance with the 2-day preliminary EMA protocol (one additional attempt allowed after re-training)\n* Current alcohol or substance abuse\n* Inability to ambulate or psychiatric conditions that prevent survey participation\n* Currently undergoing cancer treatment or received chemotherapy within the past 6 months",true,"ALL","60 Years",{"count":59,"type":60},180,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea. The main questions it aims to answer are:\n\nDoes daily psychological stress measured in real-time affect short-term and long-term cognitive function in older adults? Do pro-inflammatory cytokines (such as CRP, IL-6, IL-10, and TNF-α) mediate the relationship between emotional stress and cognitive decline? How do social support and social isolation influence cognitive function and inflammatory biomarkers over time?\n\nParticipants will:\n\nComplete baseline surveys assessing depression, cognitive function, and personal characteristics Use a smartphone app to answer brief surveys about their emotions, cognitive performance, and social interactions 1-6 times daily for two weeks Wear a Galaxy Watch to track sleep quality, heart rate, and physical activity Provide blood samples for inflammatory biomarker analysis Return for follow-up assessments at 6 months and 1 year\n\nThis study is part of an international collaboration to establish a Korean cohort comparable to the U.S. Einstein Aging Study, with the aim of developing culturally tailored dementia prevention strategies.",[64,65,66,67],"Mild Cognitive Impairment (MCI)","Dementia Alzheimer Type","Chronic Pain","Depression - Major Depressive Disorder",[69,70,71,72,73,74,75,76,77],"mild cognitive impairment","dementia","chronic pain","depression","cognitive aging","longitudinal cohort","digital biomarkers","dementia biomarkers","behavioral phenotyping","2026-03-16",{"date":80,"type":81},"2026-03-20","ACTUAL",{"date":83,"type":81},"2025-04-01",{"date":85,"type":60},"2037-12-31",{"name":5,"class":6},1]