[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100377980":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":52,"collaborators":55,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":82,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8],{"label":9,"type":10,"description":9,"interventionNames":11},"Middle-aged and Older adults with Prediabetes",null,[12],"Device: Continuous Glucose Monitoring System (CGMS)",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","Continuous Glucose Monitoring System (CGMS)","Continuous Glucose Monitoring System (CGMS)- minimally invasive sensors that measure glucose concentrations at 5-min intervals over several days.",[9],[20],{"name":21,"affiliation":22,"role":23},"Tasneem Khambaty, PhD","University of Maryland, Baltimore County","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Kathleen Simpson","CONTACT","4106057179","Kathleen.Simpson@va.gov",{"name":31,"role":27,"phone":10,"phoneExt":10,"email":32},"Ashley Splain, BA","asplain1@umbc.edu",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Baltimore VA Geriatric Research Education and Clinical Center (GRECC)","RECRUITING","Baltimore","Maryland","21201","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-76.61219,39.29038,{"lat":46,"lon":45},[49],{"name":21,"role":27,"phone":50,"phoneExt":10,"email":51},"410-455-2304","khambaty@umbc.edu",{"type":23,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Leslie Katzel","Associate Professor",[56,59],{"name":57,"class":58},"Baltimore VA Medical Center","FED",{"name":22,"class":6},"100377980","glucose-variability-and-cognition-in-prediabetes-100377980",false,"NCT04201600","Glucose Variability and Cognition in Prediabetes","Relations of Glucose Variability with Cognitive Function and Functional Status Among Older Adults At Risk for Diabetes","Inclusion Criteria:\n\n* Aged 50 years and older\n* At least 8th grade education\n\nExclusion Criteria:\n\n* Diagnosed type 1 or type 2 diabetes\n* Current use of mediation for diabetes (oral hypoglycemic agents, insulin), or with diabetic properties (e.g., steroids)\n* Chronic disorders (cardiovascular disease, peripheral vascular disease, stroke, transient ischemic attack, chronic kidney disease, past year cancer)\n* Neurological disorders (e.g., Parkinson's, epilepsy, multiple sclerosis)\n* History of dementia or suspected dementia\n* Known HIV\n* Serious mental illness, psychosis, or use of psychotropic medication\n* Heavy alcohol use",true,"ALL","50 Years",{"count":71,"type":72},30,"ESTIMATED","OBSERVATIONAL","This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.",[76,77,78,79,80,81],"Glucose Metabolism Disorders (Including Diabetes Mellitus)","Cognitive Decline","Functional Status","PreDiabetes","Aging","Depression",[83,16,84,80,85,86,77],"Glucose Variability","Prediabetes","Physical Functioning","Neurocognition","2025-03-25",{"date":89,"type":90},"2025-03-30","ACTUAL",{"date":92,"type":90},"2022-03-01",{"date":94,"type":72},"2026-12-31",{"name":5,"class":6},1]