[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641973":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":30,"centralContacts":39,"locations":48,"responsibleParty":66,"collaborators":30,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":30,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":30,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":51,"whyStopped":30,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Hasan Kalyoncu University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Gluten-Free Diet Group","EXPERIMENTAL","Participants will follow a gluten-free diet for 12 weeks. All gluten-containing foods will be eliminated, and dietary guidance will be provided throughout the intervention period.",[13],"Behavioral: Gluten-Free Diet Group",{"label":15,"type":10,"description":16,"interventionNames":17},"Mediterranean Diet Group","Participants will follow a Mediterranean diet for 12 weeks, emphasizing high intake of fruits, vegetables, whole grains, legumes, olive oil, and fish, with limited processed foods.",[18],"Behavioral: Mediterranean Diet",{"label":20,"type":21,"description":22,"interventionNames":23},"Control Diet Group","ACTIVE_COMPARATOR","Participants will continue their usual diet without specific dietary modifications. General dietary advice may be provided but no structured intervention will be implemented.",[24],"Behavioral: Control Diet",[26,31,35],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Participants will follow a gluten-free diet in which all wheat, barley, rye, and their derivatives are eliminated for 12 weeks. The diet focuses on naturally gluten-free foods such as fruits, vegetables, legumes, meat, fish, rice, and corn.",[9],null,{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Mediterranean Diet","Participants will follow a Mediterranean dietary pattern characterized by high intake of fruits, vegetables, whole grains, legumes, olive oil, and fish, with moderate consumption of dairy and low intake of red meat and processed foods for 12 weeks.",[15],{"type":27,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Control Diet","Participants will continue their habitual diet without any specific dietary restrictions or structured dietary guidance during the 12-week study period.",[20],[40,45],{"name":41,"role":42,"phone":43,"phoneExt":30,"email":44},"Nilüfer Gürsel, PhD","CONTACT","+90 506 379 73 42","nilufergursell@gmail.com",{"name":46,"role":42,"phone":30,"phoneExt":30,"email":47},"Mine Yurttagül, Prof. Dr.","mine@yurttagul.com",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":30,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"NCR International Hospital","RECRUITING","Gaziantep","Şehitkamil","27560","Turkey (Türkiye)",{"type":57,"coordinates":58},"Point",[59,60],37.3825,37.05944,{"lat":60,"lon":59},[63,64],{"name":41,"role":42,"phone":43,"phoneExt":30,"email":44},{"name":41,"role":65,"phone":30,"phoneExt":30,"email":30},"PRINCIPAL_INVESTIGATOR",{"type":65,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Nilüfer Gürsel","Principal Investigator","100641973","gluten-free-vs-mediterranean-diet-in-rheumatoid-arthritis-100641973",false,"NCT07646262","Gluten-Free vs Mediterranean Diet in Rheumatoid Arthritis","Investigation of the Effects of a Gluten-Free Diet and the Mediterranean Diet on the Inflammatory Index, Disease Activity, and Quality of Life in Patients With Rheumatoid Arthritis.","Inclusion Criteria:\n\nDiagnosis of rheumatoid arthritis according to ACR\u002FEULAR criteria Age between 19-65 years Stable medication regimen for at least 3 months prior to enrollment Willingness to comply with dietary interventions and study procedures Ability to provide informed consent\n\nExclusion Criteria:\n\nPregnancy or lactation Presence of other autoimmune or inflammatory diseases (e.g., SLE, IBD) Severe comorbidities (e.g., advanced cardiovascular, renal, or hepatic disease) Use of special diets (e.g., gluten-free diet) in the last 3 months Recent change in biologic or corticosteroid therapy (\\\u003C3 months) Food allergies or intolerances affecting dietary intervention adherence Inability to comply with dietary protocol or follow-up visits","ALL","19 Years","65 Years",{"count":80,"type":81},66,"ESTIMATED","INTERVENTIONAL",[84],"NA","This study aims to evaluate the effects of different dietary interventions, including gluten-free, Mediterranean, and control diets, on disease activity, quality of life, and dietary inflammatory index in patients with rheumatoid arthritis. Participants will be followed for 12 weeks, and changes in clinical and nutritional outcomes will be assessed.",[87],"Rheumatoid Arthritis (RA",[89,90,91,92,93],"Rheumatoid arthritis","Mediterranean diet","Gluten-free diet","Dietary inflammatory index (DII)","Disease activity (DAS28)","2026-06-09",{"date":96,"type":97},"2026-06-12","ACTUAL",{"date":99,"type":97},"2025-10-29",{"date":101,"type":81},"2026-08-31",{"name":5,"class":6},1]