[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615276":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":47,"collaborators":25,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":25,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":35,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Kasr El Aini Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"G group","EXPERIMENTAL","Gradual group (G group) deflation by rate 50mmHg\u002F 30s until complete release within 3 minutes",[13],"Device: Tourniquet deflation",{"label":15,"type":16,"description":17,"interventionNames":18},"I group","ACTIVE_COMPARATOR","Intermittent group (I group) complete deflation will occur for 10 seconds, then reinflated for 50 seconds, repeating this cycle three times until complete release.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Tourniquet deflation","Tourniquet deflation technique",[9,15],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Khaled Sarhan, MD","CONTACT","+201020067816","khaled.sarhan@kasralainy.edu.eg",[33],{"facility":34,"status":35,"city":36,"state":25,"zip":25,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Cairo university hospitals","RECRUITING","Cairo","Egypt","EG",{"type":40,"coordinates":41},"Point",[42,43],31.24967,30.06263,{"lat":43,"lon":42},[46],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Khaled Abdelfattah Abdallah Sarhan","principal investigator, Associate professor of anesthesia, Cairo university","100615276","gradual-versus-intermittent-release-of-tourniquet-effect-on-map-in-hypertensive-patients-undergoing-upper-limb-orthopedic-surgeries-100615276",false,"NCT07290504","Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries","The Effect of Gradual Versus Intermittent Release of Tourniquet on Mean Arterial Blood Pressure in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries: A Blinded Randomized Controlled Study","Inclusion Criteria:\n\n* Hypertensive patients (controlled on medical treatment more than three months)\n* Patients scheduled for upper limb orthopedic surgeries using a tourniquet for at least 30 min.\n* BMI from 18.5 to 29.9\n\nExclusion Criteria:\n\n* Patient refusal\n* ASA physical status \\> II\n* Multiple orthopedic surgeries\n* Emergency surgeries\n* Patient with relative contraindications for tourniquet use","ALL","18 Years","65 Years",{"count":62,"type":63},68,"ESTIMATED","INTERVENTIONAL",[66],"NA","In this clinical trial, the authors will compare two tourniquet deflation techniques and their clinical implications on hemodynamics and acid base parameters in hypertensive orthopedic patients undergoing upper limb surgeries under general anesthesia.",[69],"Hemodynamics",[71,72,73,74,75],"Mean arterial pressure","Acid base","Tourniquet","Orthopedics","Hypertension","2025-12-17",{"date":78,"type":79},"2025-12-18","ACTUAL",{"date":81,"type":79},"2025-12-13",{"date":83,"type":63},"2026-05",{"name":5,"class":6},1]