[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578262":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":39,"responsibleParty":62,"collaborators":64,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":24,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":95,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Etablissement Français du Sang","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Whole blood","Participants in this arm donate whole blood",[12],"Biological: Whole blood donation",{"label":14,"type":6,"description":15,"interventionNames":16},"Apheresis","Participants in this arm make a plasma\u002Fplatelet apheresis donation",[17],"Biological: Apheresis donation",[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BIOLOGICAL","Whole blood donation","This intervention involves the collection of a whole blood bag.",[9],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Apheresis donation","This procedure involves the collection of a plasma\u002Fplatelets bag by apheresis",[14],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Hind HAMZEH-COGNASSE, PhD, HDR","CONTACT","+33 477 421 400","hind.hamzeh@univ-st-etienne.fr",{"name":36,"role":32,"phone":37,"phoneExt":24,"email":38},"Fabrice COGNASSE, PhD, HDR","+33 683 975 883","fabrice.cognasse@efs.sante.fr",[40],{"facility":41,"status":42,"city":43,"state":24,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Maison du don de l'EFS Auvergne Rhônes-Alpes","RECRUITING","Saint-Etienne","42100","France","FR",{"type":48,"coordinates":49},"Point",[50,51],4.39,45.43389,{"lat":51,"lon":50},[54,58],{"name":55,"role":32,"phone":56,"phoneExt":24,"email":57},"Patricia CHAVARIN, MD","+33 477 814 242","patricia.chavarin@efs.sante.fr",{"name":59,"role":32,"phone":60,"phoneExt":24,"email":61},"Franck BERNAUD, MD","+33 477 814 243","franck.bernaud@efs.sante.fr",{"type":63,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[65,68],{"name":66,"class":67},"Centre de transfusion sanguine des Armées, Clamart, France","UNKNOWN",{"name":69,"class":67},"INSERM, SAINBIOSE U1059","100578262","group-o-whole-blood--storage-lesion-impact-and-inflammation-100578262",false,"NCT06809010","grouP O wholE blooD : storagE leSion impacT And infLammation","grouP O wholE blooD (LTO-WB): storagE leSion impacT And infLammation","PEDESTAL EFS","Inclusion Criteria:\n\nSelf-referred donors eligible for blood donation (whole blood and\u002For platelet\u002Fplasma apheresis), meeting the following inclusion criteria:\n\n* Be in good health\n* Weigh at least 50 kg\n* Must be between 18 and 70 years of age for whole blood donation and between 18 and 65 years of age for plasma\u002Fplatelet donation by apheresis.\n\nExclusion Criteria:\n\nSubjects ineligible to donate blood",true,"ALL","18 Years","65 Years",{"count":83,"type":84},30,"ESTIMATED","INTERVENTIONAL",[87],"NA","\"Etablissement Français du Sang\" (EFS) prepares labile blood products from blood donations that are separated by type (red blood cells, plasma and platelets).\n\nThe \"Centre de Transfusion Sanguine des Armées\" (CTSA) produces an innovative labile blood product, LTO-WB, corresponding to group O leukocyte-free whole blood.\n\nThe objective of the PEDESTAL EFS study is to compare the inflammatory and biological characteristics of blood products prepared by the EFS vs. the labile blood product prepared by the CTSA.",[90,91,92,93,94],"Blood Donation","Blood Platelets","Blood Donors","Inflammation","Transfusion",[96,97,98,99,100,101,102,103,104,105],"blood","LTO-WB","characterization of labile blood products","whole blood","apheresis","plasma","platelet","red blood cells","inflammation","transfusion","2025-08-04",{"date":108,"type":109},"2025-08-06","ACTUAL",{"date":111,"type":109},"2025-03-12",{"date":113,"type":84},"2028-02",{"name":5,"class":6},1]