[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100314454":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":17,"responsibleParty":33,"collaborators":7,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":7,"studyType":49,"phases":7,"briefSummary":50,"conditions":51,"keywords":7,"overallStatus":20,"whyStopped":7,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},{"fullName":5,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Jie Jia, PhD","PRINCIPAL_INVESTIGATOR",[13],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","0086-13122322289","jie.jia@shsmu.edu.cn",[18],{"facility":19,"status":20,"city":21,"state":7,"zip":7,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Department of NICU, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","RECRUITING","Shanghai","China","CN",{"type":25,"coordinates":26},"Point",[27,28],121.45806,31.22222,{"lat":28,"lon":27},[31],{"name":10,"role":14,"phone":32,"phoneExt":7,"email":16},"008613122322289",{"type":34,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100314454","gut-microbiota-of-preterm-infants-and-full-term-infants-at-early-life-100314454",false,"NCT03373721","Gut Microbiota of Preterm Infants and Full-term Infants at Early Life","Gut Microbial Succession of Preterm Infants and Full-term Infants at Early Life","Inclusion Criteria:\n\nPreterm infants\n\n1. gestational age \\\u003C37 weeks;\n2. no gastrointestinal tract disorders, metabolic diseases, or viral hepatitis;\n3. hospital stay \\> 7 days;\n\nExclusion criteria:\n\n1. NICU stay less than 7 days\n2. Necrotizing enterocolitis infant\n\nControl group:\n\n1. Full-term healthy infants;\n2. gestational age \\>37 weeks;\n3. vaginally born;\n4. no gastrointestinal tract disorders, metabolic diseases, or viral hepatitis.",true,"ALL","1 Day","4 Months",{"count":47,"type":48},102,"ESTIMATED","OBSERVATIONAL","The aim of this study is to obtain a longitudinal view of the gut microbial establishment of a cohort of 51 preterm (PT) infants compared to 50 full-term (FT) infants from birth to 90 days of age, and to identify key clinical factors that affect the establishment of neonatal microbiome.\n\nThe hypothesis of the investigators is that the gut microbiota progression of PT group and FT group is different in diversity and composition. Antibiotics and its usage duration is likely the main factor disturbing the colonization and development of the gut microbiome of PT infants.",[52,53],"Preterm Infant","Gut Microbiome","2024-04-16",{"date":56,"type":57},"2024-04-17","ACTUAL",{"date":59,"type":57},"2014-07-20",{"date":61,"type":48},"2028-12-20",{"name":5,"class":6},1]