[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639705":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"The Second Hospital of Nanjing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment","EXPERIMENTAL","Participants will receive 250mL of oxygen (30%) through a deep intestinal catheterization four times a day for 5 days",[13],"Other: Oxygen 30 %",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","PLACEBO_COMPARATOR","Participants will receive 250mL of air through a deep intestinal catheterization four times a day for 5 days.",[19],"Other: Air",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Oxygen 30 %","Patients will receive 250mL of oxygen (30%) through a deep intestinal catheterization four times a day for 5 days.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Air","Patients will receive 250mL of air through a deep intestinal catheterization four times a day for 5 days.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Faming Zhang, PhD","CONTACT","086-25-58509883","fzhang@njmu.edu.cn",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"The Second Affiliated Hospital of Nanjing Medical University","RECRUITING","Nanjing","Jiangsu","210011","China","CN",{"type":46,"coordinates":47},"Point",[48,49],118.77778,32.06167,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":34,"phoneExt":25,"email":35},"Faming Zhang, Professor",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Faming Zhang","Professor","100639705","gut-oxygen-therapy-for-ischemic-hypoxic-bowel-disease-100639705",false,"NCT07621367","Gut Oxygen Therapy for Ischemic-Hypoxic Bowel Disease","Efficacy and Safety of Gut Oxygen Therapy for Ischemic-Hypoxic Bowel Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study","Inclusion Criteria:\n\n* Clinical diagnosis of intestinal ischemia and hypoxia-related diseases caused by conditions such as ischemic bowel disease, heart failure, etc., presenting with recurrent or persistent abdominal pain and\u002For distension, and difficulty in defecation. Examples include: heart failure-related defecation difficulty, severe malnutrition combined with defecation difficulty, acute ischemic bowel disease, and chronic ischemic bowel disease.\n* At least able to perform bedside activities and able to defecate in conventional positions (sitting or squatting).\n* Age ≥18 years, and able to voluntarily sign informed consent.\n\nExclusion Criteria:\n\n* Acute intestinal emergencies such as acute intestinal obstruction, intestinal perforation, or active massive gastrointestinal bleeding.\n* Intestinal fistula.\n* History of abdominal surgery within the recent past (\\\u003C1 month).\n* Severe uncontrolled arrhythmia or respiratory failure.\n* Cardiac function Class IV (NYHA Class IV).\n* Patients with abnormal visceral pressure sensitivity.\n* Inability to cooperate with study assessments.\n* Other conditions that, in the opinion of the investigator, make the subject unsuitable for inclusion.","ALL","18 Years",{"count":68,"type":69},90,"ESTIMATED","INTERVENTIONAL",[72],"NA","This multicenter, randomized, double-blind, placebo-controlled clinical trial aimed to investigate the efficacy and safety of gut oxygen therapy in the treatment of ischemic-hypoxic bowel disease using deep intestinal catheterization as a targeted route for gut oxygen delivery.",[75,76],"Ischemic Bowel Disease","Hypoxic Events",[78,79,80,81,82],"ischemic bowel disease","heart failure","abdominal pain","abdominal distension","difficult defecation","2026-06-01",{"date":85,"type":86},"2026-06-02","ACTUAL",{"date":88,"type":69},"2026-05-28",{"date":90,"type":69},"2031-05-19",{"name":5,"class":6},1]