[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100432696":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":28,"locations":33,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Universitätsklinikum Hamburg-Eppendorf","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"TMVR",null,"Patients undergoing Transcatheter Mitral Valce Replacement (TMVR)",{"label":13,"type":10,"description":14,"interventionNames":10},"TEER","Patients undergoing mitral Transcatheter Edge-to-Edge Repair (TEER) after screening for TMVR",{"label":16,"type":10,"description":17,"interventionNames":10},"Surgery","Patients undergoing mitral valve surgery (repair or replacement) after screening for TMVR",{"label":19,"type":10,"description":20,"interventionNames":10},"Medical therapy","Patients undergoing medical therapy after screening for TMVR",[22,26],{"name":23,"affiliation":24,"role":25},"Sebastian Ludwig, MD","University Heart and Vascular Center Hamburg","PRINCIPAL_INVESTIGATOR",{"name":27,"affiliation":24,"role":25},"Edith Lubos, MD",[29],{"name":23,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","+49-40-7410-0","se.ludwig@uke.de",[34],{"facility":24,"status":35,"city":36,"state":10,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Hamburg","20246","Germany","DE",{"type":41,"coordinates":42},"Point",[43,44],9.99302,53.55073,{"lat":44,"lon":43},[47,48,50],{"name":23,"role":30,"phone":10,"phoneExt":10,"email":10},{"name":49,"role":30,"phone":10,"phoneExt":10,"email":10},"Daniel Kalbacher, MD",{"name":27,"role":25,"phone":10,"phoneExt":10,"email":10},{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100432696","hamburg-transcatheter-mitral-valve-replacement-registry-100432696",false,"NCT04914468","Hamburg TranscathEteR Mitral Valve REplacement RegiStry","Hamburg Transcatheter Mitral Valve Replacement Registry","HERMES","Inclusion Criteria:\n\n* Ability to provide written informed consent in accordance with Good Epidemiological Practice and local legislation.\n* Individuals over the age of 18 years.\n* Patients with clinically relevant mitral valve disease, who undergo screening for TMVR.\n\nExclusion Criteria:\n\n* Insufficient knowledge of the German language, to understand study documents and interview without translation\n* Physical or psychological incapability to cooperate in the investigation","ALL","18 Years","110 Years",{"count":65,"type":66},300,"ESTIMATED","OBSERVATIONAL","The Hamburg TranscathEteR Mitral Valve REplacement RegiStry (HERMES) is a prospective clinical cohort registry aiming to gather follow-up information on short- and long-term outcome of patients with mitral valve disease that undergo transcatheter mitral valve replacement (TMVR) screening. In particular, long-term durability and function of implanted bioprosteses is of utmost interest for both patients and clinicians. Moreover, this study aimes to investigate and compare the different treatment strategies patients undergo after successful or unsuccessful screening for TMVR.",[70],"Mitral Valve Disease","2021-06-02",{"date":73,"type":74},"2021-06-04","ACTUAL",{"date":76,"type":74},"2021-03-08",{"date":78,"type":66},"2030-12-31",{"name":5,"class":6},1]