[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512984":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":37,"centralContacts":38,"locations":44,"responsibleParty":61,"collaborators":63,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":37,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":37,"enrollmentInfo":76,"targetDuration":37,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":37,"overallStatus":46,"whyStopped":37,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8,14,18,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"left DLPFC stimulation","EXPERIMENTAL","HD-tDCS will be used to deliver direct current to the target via rubber electrodes and HD-tDCS gels. The 9 electrodes (8 channels + 1 ground) positions and current intensity will be determined based on computer simulation using HDTargets software (Soterix Inc.) that results in maximum focal current on the left dorsolateral prefrontal cortex (DLPFC; x=-44, y=10, z=30) with inward field orientation. The peak current will not exceed 2 mA. A constant current will be delivered for 20 minutes.",[13],"Device: high definition transcranial direct current stimulation (HD-tDCS)",{"label":15,"type":10,"description":16,"interventionNames":17},"right DLPFC stimulation","HD-tDCS will be used to deliver direct current to the target via rubber electrodes and HD-tDCS gels. The 9 electrodes (8 channels + 1 ground) positions and current intensity will be determined based on computer simulation using HDTargets software (Soterix Inc.) that results in maximum focal current on the right dorsolateral prefrontal cortex (DLPFC; x=+42, y=+14, z=+30) with inward field orientation. The peak current will not exceed 2 mA. A constant current will be delivered for 20 minutes.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"left IPL stimulation","HD-tDCS will be used to deliver direct current to the target via rubber electrodes and HD-tDCS gels. The 9 electrodes (8 channels + 1 ground) positions and current intensity will be determined based on computer simulation using HDTargets software (Soterix Inc.) that results in maximum focal current on the left intraparietal lobe (IPL; x=-50, y=-36, z=+42) with inward field orientation. The peak current will not exceed 2 mA. A constant current will be delivered for 20 minutes.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"VLPFC-PCC stimulation","HD-tDCS will be used to deliver direct current to the target via rubber electrodes and HD-tDCS gels. The 9 electrodes (8 channels + 1 ground) positions and current intensity will be determined based on computer simulation using HDTargets software (Soterix Inc.) that results in maximum focal current on the left ventrolateral prefrontal cortex (VLPFC; x=-50, y=+26, z=+8) and posterior cingulate cortex (PCC; x=1, y=-61, z=38) with inward field orientation. The peak current will not exceed 2 mA. A constant current will be delivered for 20 minutes.",[13],{"label":27,"type":28,"description":29,"interventionNames":30},"Sham stimulation","SHAM_COMPARATOR","One of the above three targets will be randomly selected. The current will be applied for 30 seconds ramp-up followed by 30 seconds ramp-down.",[13],[32],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"DEVICE","high definition transcranial direct current stimulation (HD-tDCS)","HD-tDCS will be provided for 20 minutes for each stimulation with peak intensity of 2mA.",[27,23,9,19,15],null,[39],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},"Ji Hyun Ko, PhD","CONTACT","2042930724","ji.ko@umanitoba.ca",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Winnipeg","Manitoba","R3E 0J9","Canada","CA",{"type":53,"coordinates":54},"Point",[55,56],-97.14704,49.8844,{"lat":56,"lon":55},[59],{"name":40,"role":41,"phone":60,"phoneExt":37,"email":43},"204-318-2566",{"type":62,"investigatorFullName":37,"investigatorTitle":37,"investigatorAffiliation":37,"oldNameTitle":37,"oldOrganization":37},"SPONSOR",[64],{"name":65,"class":6},"Natural Sciences and Engineering Research Council, Canada","100512984","hd-tdcs-to-modulate-connectivity-100512984",false,"NCT05959551","HD-tDCS to Modulate Connectivity","Modulating Functional Brain Connectivity Using High Definition Transcranial Direct Current Stimulation (HD-tDCS)","Inclusion Criteria:\n\n\\- All other than excluded.\n\nExclusion Criteria:\n\n* History or susceptibility to any neurological or psychiatric diseases, particularly seizures\n* abnormal MRI\n* metal implants or a cardiac pacemaker\n* pregnant or breastfeeding women",true,"ALL","18 Years",{"count":77,"type":78},100,"ESTIMATED","INTERVENTIONAL",[81],"NA","The purpose of the proposed study is to broaden our understanding on the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) so that its clinical effects can be further improved.",[84],"Electricity; Effects","2026-04-27",{"date":87,"type":88},"2026-05-01","ACTUAL",{"date":90,"type":88},"2023-07-01",{"date":92,"type":78},"2026-08-31",{"name":5,"class":6},1]