[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643981":3},{"organization":4,"armGroups":7,"interventions":37,"overallOfficials":50,"centralContacts":55,"locations":60,"responsibleParty":77,"collaborators":42,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":42,"enrollmentInfo":91,"targetDuration":42,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":114,"overallStatus":62,"whyStopped":42,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":146},{"fullName":5,"class":6},"Longevity Metrics, Inc.","INDUSTRY",[8,14,19,24,28,33],{"label":9,"type":10,"description":11,"interventionNames":12},"Static Personalized Health Report","ACTIVE_COMPARATOR","Participants complete comprehensive multi-system health screening and receive a standard static personalized health report.",[13],"Behavioral: Interactive Personalized Health Report",{"label":15,"type":16,"description":17,"interventionNames":18},"Interactive Personalized Health Report","EXPERIMENTAL","Participants complete identical comprehensive multi-system health screening and receive an interactive personalized report allowing real-time adjustment of behaviors and diagnostic inputs to visualize projected changes in composite scores, estimated biological age, and aging trajectory.",[13],{"label":20,"type":10,"description":21,"interventionNames":22},"Fixed-Lab Health Screenings","Health screenings performed at fixed-lab site.",[23],"Behavioral: Mobile Community-Based Health Screenings",{"label":25,"type":16,"description":26,"interventionNames":27},"Mobile Lab Health Screenings","Health screenings performed in remote locations using a mobile lab",[23],{"label":29,"type":10,"description":30,"interventionNames":31},"Human Delivered Health Screenings","Health screenings delivered by human operators only",[32],"Behavioral: Hybrid Medical Droid and Human Delivered Health Screenings",{"label":34,"type":16,"description":35,"interventionNames":36},"Hybrid Medical Droid and Human Delivered Health Screenings","Health screenings delivered by a hybrid model using medical droid and human operators",[32],[38,43,47],{"type":39,"name":15,"description":40,"armGroupLabels":41,"otherNames":42},"BEHAVIORAL","Static versus interactive health report",[15,9],null,{"type":39,"name":44,"description":45,"armGroupLabels":46,"otherNames":42},"Mobile Community-Based Health Screenings","Mobile versus Fixed Laboratory Health Screenings",[20,25],{"type":39,"name":34,"description":48,"armGroupLabels":49,"otherNames":42},"Hybrid Medical Droid and Human Delivered versus Human-Only Delivered Health Screenings",[29,34],[51],{"name":52,"affiliation":53,"role":54},"William Brandenburg, MD","Longevity Metrics","PRINCIPAL_INVESTIGATOR",[56],{"name":52,"role":57,"phone":58,"phoneExt":42,"email":59},"CONTACT","13035010016","info@longevitymetrics.org",[61],{"facility":53,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"RECRUITING","Boulder","Colorado","80301","United States","US",{"type":69,"coordinates":70},"Point",[71,72],-105.27055,40.01499,{"lat":72,"lon":71},[75],{"name":52,"role":57,"phone":76,"phoneExt":42,"email":59},"3035010016",{"type":78,"investigatorFullName":52,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"SPONSOR_INVESTIGATOR","Principal Investigator","100643981","health-ahead-comparative-effectiveness-study-100643981",false,"NCT07669168","Health Ahead Comparative Effectiveness Study","Health Ahead: Sequential Comparative-Effectiveness Studies Toward Automated, Universally Deployable Preventive Health Screening","HACE","Inclusion Criteria:\n\n* Age 18 years or older\n* Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative\n* Willing to participate in longitudinal follow-up.\n\nExclusion Criteria:\n\n\\- Age under 18 years.",true,"ALL","18 Years",{"count":92,"type":93},1000000,"ESTIMATED","INTERVENTIONAL",[96],"NA","The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening - each isolated as a single variable against current practice - on the path toward a fully automated screening system deployable in any environment, including the most isolated and resource-limited communities. Each comparison is evaluated with a common set of engagement, behavior-change, experience, cost, and longitudinal outcome measures, allowing results to accumulate on a consistent yardstick across the life of the platform.\n\nThe first comparison evaluates static versus interactive personalized health report delivery. Subsequent pre-planned comparisons, added by protocol amendment, evaluate mobile community versus fixed laboratory screening; and a hybrid medical-droid plus human-delivery model versus human-only screening. All participants are simultaneously enrolled in the 100-Year Human Aging Study and the Human Observatory Study, contributing individual longitudinal and population-level causal inference data through those protocols.",[99,100,101,102,103,104,105,106,107,108,109,110,111,112,113],"Health Services Accessibility","Rural Health","Medically Underserved Area","Preventive Health Services","Patient Participation","Health Behavior","Aging","Cardiovascular Diseases","Metabolic Syndrome","Cognitive Dysfunction","Frailty","Activities of Daily Living","Health Related Quality of Life","Health Equity","Telemedecine",[115,116,117,118,119,112,100,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136],"Sequential Platform Trial","Interactive Health Report","Health Activation","Mobile Health Screening","Comparative Effectiveness","Medically Underserved","Preventive Medicine","Patient Engagement","Cardiopulmonary Exercise Testing","Body Composition","DEXA","Health Ahead Bus","Mobile Clinic","Automated Screening","Medical Droids","Biological Age","Healthspan","Longevity","Life Expectancy","Chronic Disease","Cost-Effectiveness","Health Services Research","2026-06-20",{"date":139,"type":140},"2026-06-25","ACTUAL",{"date":142,"type":93},"2026-06-09",{"date":144,"type":93},"2099-12-31",{"name":52,"class":6},1]