[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573654":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":48,"centralContacts":52,"locations":62,"responsibleParty":81,"collaborators":34,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":34,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":105,"overallStatus":108,"whyStopped":34,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Filtered Air (FA)","PLACEBO_COMPARATOR","Participants will be exposed to 2 hours of high-efficiency particulate air (HEPA) filtered air (FA).",[13],"Other: Filtered Air (FA)",{"label":15,"type":16,"description":17,"interventionNames":18},"Wood Smoke (WS)","ACTIVE_COMPARATOR","Participants will be exposed to 2 hours of controlled wood smoke (WS) standardized to 300ug\u002Fm\\^3 of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).",[19],"Other: Wood Smoke (WS)",{"label":21,"type":16,"description":22,"interventionNames":23},"Diesel Exhaust (DE)","Participants will be exposed to 2 hours of controlled diesel exhaust (DE) as a model of traffic-related air pollution (TRAP) standardized to 300ug\u002Fm\\^3 of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).",[24],"Other: Diesel Exhaust (DE)",{"label":26,"type":16,"description":27,"interventionNames":28},"Diesel Exhaust and Wood Smoke (DEWS)","Participants will be exposed to 2 hours of combined controlled diesel exhaust (DE) and wood smoke (DEWS) standardized to 300ug\u002Fm\\^3 of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).",[29],"Other: Diesel Exhaust and Wood Smoke (DEWS)",[31,35,38,43],{"type":6,"name":9,"description":32,"armGroupLabels":33,"otherNames":34},"Exposure to HEPA filtered air, as a control",[9],null,{"type":6,"name":15,"description":36,"armGroupLabels":37,"otherNames":34},"Wood smoke (WS) standardized to 300µg\u002Fm³ of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).",[15],{"type":6,"name":21,"description":39,"armGroupLabels":40,"otherNames":41},"Diesel exhaust (DE) standardized to 300µg\u002Fm³ of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).",[21],[42],"Traffic-Related Air Pollution",{"type":6,"name":26,"description":44,"armGroupLabels":45,"otherNames":46},"Combined diesel exhaust and wood smoke standardized to 300µg\u002Fm³ of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).",[26],[47],"Air Pollution",[49],{"name":50,"affiliation":5,"role":51},"Chris Carlsten, MD","PRINCIPAL_INVESTIGATOR",[53,59],{"name":54,"role":55,"phone":56,"phoneExt":57,"email":58},"Agnes Yuen","CONTACT","604-875-4111","66455","agnes.yuen@ubc.ca",{"name":60,"role":55,"phone":61,"phoneExt":34,"email":34},"Parteek Johal","604-875-5132",[63],{"facility":5,"status":34,"city":64,"state":65,"zip":66,"country":67,"countryCode":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"Vancouver","British Columbia","V5Z 1M9","Canada","CA",{"type":70,"coordinates":71},"Point",[72,73],-123.11934,49.24966,{"lat":73,"lon":72},[76,78],{"name":77,"role":55,"phone":56,"phoneExt":57,"email":58},"Agnes Yuen, BSc",{"name":79,"role":55,"phone":61,"phoneExt":34,"email":80},"PJ Johal, BSc","p.johal@ubc.ca",{"type":51,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"Christopher Carlsten","Professor","100573654","health-effects-of-wood-smoke-and-traffic-related-air-pollution-exposures-a-necessary-comparison-100573654",false,"NCT06749093","Health Effects of Wood Smoke and Traffic-Related Air Pollution Exposures: a Necessary Comparison","WADE","Inclusion Criteria:\n\n* Age 19-40\n* Healthy, with no history of respiratory disease\n* Lifetime non-smoker and non-vaper.\n\nExclusion Criteria:\n\n* Pregnant, planning to become pregnant, or breastfeeding during the study period (confirmed through pregnancy tests at each visit if applicable)\n* Frequent WS or DE exposures (e.g. home fireplace used for heating\u002Fcooking, or employment in transportation, mining, or as a firefighter).",true,"ALL","19 Years","40 Years",{"count":96,"type":97},48,"ESTIMATED","INTERVENTIONAL",[100],"NA","Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time. However, there is little data comparing the effects of different types of air pollution on health. In Canada, traffic-related air pollution and wood smoke (wildfires and wood burning for heating) are very common air pollutants. This study aims to safely complete a controlled human exposure study to test how these air pollution types acutely affect health.",[103,104],"Healthy Individuals","Allergic Rhinitis",[47,106,107],"Wood Smoke","Diesel Exhaust","NOT_YET_RECRUITING","2024-12-17",{"date":111,"type":112},"2024-12-27","ACTUAL",{"date":114,"type":97},"2025-07-01",{"date":116,"type":97},"2029-12-31",{"name":5,"class":6},1]