[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610413":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":24,"locations":30,"responsibleParty":47,"collaborators":23,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":23,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":23,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":33,"whyStopped":23,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University of California, Davis","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pecan nut then no nut","EXPERIMENTAL","Participant will add pecan nuts to their diet during the first intervention arm, then they will cross over to the no nut diet arm",[13],"Other: pecan nut",{"label":15,"type":10,"description":16,"interventionNames":17},"No nut then pecan nut","Participant will consume a diet without nuts during the first intervention arm, then they will cross over to the arm where they will add pecan nuts to their diet.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"pecan nut","Dose - 2 ounces of pecan nuts, daily",[15,9],null,[25],{"name":26,"role":27,"phone":28,"phoneExt":23,"email":29},"Francene Steinberg, PhD","CONTACT","530-752-0160","fmsteinberg@ucdavis.edu",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Ragle Human Nutrition Center, UC Davis campus","RECRUITING","Davis","California","95616","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-121.74052,38.54491,{"lat":43,"lon":42},[46],{"name":26,"role":27,"phone":28,"phoneExt":23,"email":29},{"type":48,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100610413","health-properties-of-pecan-nut-consumption-100610413",false,"NCT07227259","Health Properties of Pecan Nut Consumption","Assessment of Systematic Health Properties of Pecan Nut Consumption: Gut, Vascular, Metabolic and Cognitive Outcomes","Inclusion Criteria:\n\nBMI of 20-35 kg\u002Fm2, ability to understand the intervention instructions, Willingness to follow the dietary intervention, Willingness to provide biological samples (blood and stool) -\n\nExclusion Criteria:\n\nAllergy to pecan or other nuts, Cognitive impairment due to dementia of any type and inability to understand or comply with intervention instructions, Use of menopausal hormone replacement therapy, Use of antibiotics or probiotics in the 2 months prior to enrollment, Uncontrolled diabetes with HbA1C of \\>9.5, Vegetarian\u002Fvegan, Any serious medical condition (such as chronic kidney disease of stage 3 or greater, heart failure, active cancer treatment, inflammatory bowel disease, etc.), Consumption of supplements that may interfere with vascular response or gut microbiome, Use of statin drugs for cholesterol lowering.\n\n\\-",true,"ALL","45 Years","75 Years",{"count":61,"type":62},40,"ESTIMATED","INTERVENTIONAL",[65],"NA","The main goal of this clinical study is to see if consuming pecan nuts will result in improvements in overall body metabolism such as in blood lipids, markers of inflammation, blood pressure, cognitive performance and changes in bacteria living in the gut in adults 45 to 75 years of age.\n\nParticipants will take part in two 3-month intervention periods, separated by 4-6 weeks, in random order ( a total of approximately 7 months). During one intervention period, they will include pecan nuts in their diet each day, while during the other intervention period they will avoid pecans in their diet. There will be an initial screening visit to evaluate eligibility and four study visits to the clinic.\n\nParticipants will be asked to complete some questionnaires about their diet, physical and cognitive health, and provide blood and stool samples, and have their blood pressure measured.",[68],"Healthy Adults",[20,70,71,72],"cardiovascular","gut microbiome","cognitive","2026-02-20",{"date":75,"type":76},"2026-02-24","ACTUAL",{"date":78,"type":76},"2025-11-15",{"date":80,"type":62},"2027-12",{"name":5,"class":6},1]