[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100455170":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":34,"responsibleParty":48,"collaborators":50,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":20,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":36,"whyStopped":20,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"KK Women's and Children's Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Study Arm","EXPERIMENTAL","The intervention will comprise four modules, namely the HELMS Journey, HELMS Model, HELMS Lifestyle and HELMS Community. The HELMS Journey will provide anticipatory guidance for both HELMS and routine clinic visits. The HELMS Model will deliver the 4S ('Screening', 'Size', 'Supplementation' and 'Specific case management') care plan, detailed below. The HELMS Lifestyle will provide lifestyle support in terms of healthy eating through the 6P tool ('Portion', 'Proportion', 'Pleasure', 'Phase', Physicality', 'Psychology'), physical activity, sleep and mental well-being. Finally, the HELMS Connection will provide community support and improve engagement with the program.",[13],"Behavioral: HELMS Lifestyle Intervention",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","HELMS Lifestyle Intervention","The HELMS life-course Interventions, namely 4S ('Screening', 'Size', 'Supplementation' and 'Specific case management'), are developed to deliver care throughout the journey from preconception to postpartum periods. Screening involves health and risk assessments through physical and biomarker measurements, as well as emotion and sleep evaluations for mother, and developmental assessment for children. Body Size management encompasses education on weight status awareness and mother-child health implications, both mother-child weight tracking, healthy eating and physical activity guidance. Supplementation includes multi-micronutrient, vitamin D, calcium and\u002For Docosahexaenoic acid (DHA) supplements, which is phase-specific for mother, and vitamin D drops supplement for child. Specific case management comprises preconception sexual health and function management, pregnancy symptoms management, postpartum recovery management, infant growth monitoring and feeding management.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Jerry Chan, MB BCh BaO MA FRCOG PhD","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Xiang Wen Ng, MPH","CONTACT","+65 6394 8113","ng.xiang.wen@kkh.com.sg",{"name":32,"role":28,"phone":20,"phoneExt":20,"email":33},"Lan Tian Lai, MSc","lai.lan.tian@kkh.com.sg",[35],{"facility":5,"status":36,"city":37,"state":20,"zip":38,"country":37,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Singapore","229899","SG",{"type":41,"coordinates":42},"Point",[43,44],103.85007,1.28967,{"lat":44,"lon":43},[47],{"name":32,"role":28,"phone":20,"phoneExt":20,"email":33},{"type":49,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[51],{"name":52,"class":53},"Lien Foundation","UNKNOWN","100455170","healthy-early-life-moments-in-singapore-100455170",false,"NCT05207059","Healthy Early Life Moments in Singapore","HELMS","Inclusion Criteria:\n\n1. Women aged 21-40 years\n2. BMI 25-40 kg\u002Fm2\n3. Intention to reside in Singapore for the next 4 years\n4. Chinese, Malay, Indian or any combination of these 3 ethnic groups\n5. Planning to conceive within 1 year\n6. Able to understand English\n7. Able to provide written, informed consent\n\nExclusion Criteria:\n\n1. Currently pregnant\n2. Known type 1 or type 2 diabetes\n3. On any anticonvulsant medication in the past 1 month\n4. On any oral steroid in the past 1 month (e.g. Prednisolone, Prednisone, Deltasone, Prelone, Methyl Prednisolone, Medrol, Hydrocortisone, Cortef, Dexamethasone, Decadron)\n5. On any oral, implanted contraception or intrauterine contraceptive device (IUCD) in situ in the past 1 month\n6. On any fertility medication (e.g. hormones injection, IVF treatments) other than Clomiphene\u002F Letrozole in the past 1 month\n7. On HIV or Hepatitis B or C medication in the past 1 month.",true,"FEMALE","21 Years","40 Years",{"count":66,"type":67},500,"ESTIMATED","INTERVENTIONAL",[70],"NA","This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health, among overweight and obese women.",[73,74,75,76],"Metabolic Disease","Mental Health Wellness 1","Lifestyle Risk Reduction","Maternal Obesity",[78,79,80],"Obesity","Mental health","Lifestyle intervention","2024-10-08",{"date":83,"type":84},"2024-10-10","ACTUAL",{"date":86,"type":84},"2022-03-18",{"date":88,"type":67},"2028-12",{"name":5,"class":6},1]