[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590026":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":34,"responsibleParty":54,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Abramson Cancer Center at Penn Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy Volunteer",null,"Females 30 or older who do not have a genetic predisposition to ovarian cancer, are unaffected by cancer, and have not had bilateral oophorectomy.",[13],"Other: Self-Administered Sample Collection",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Self-Administered Sample Collection","Participants will collect vaginal swabs and a stool sample.",[9],[20],{"name":21,"affiliation":22,"role":23},"Susan Domchek, MD","University of Pennsylvania","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Catherine Wolfe, BA","CONTACT","215-360-0422","catherine.wolfe@pennmedicine.upenn.edu",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Jamie Brower, MS","215-662-7245","jabrower@pennmedicine.upenn.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Abramson Cancer Center of the University of Pennsylvania","RECRUITING","Philadelphia","Pennsylvania","19104","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-75.16362,39.95238,{"lat":47,"lon":46},[50,53],{"name":21,"role":27,"phone":51,"phoneExt":10,"email":52},"855-216-0098","PennCancerTrials@emergingmed.com",{"name":21,"role":23,"phone":10,"phoneExt":10,"email":10},{"type":55,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100590026","healthy-volunteers-study-100590026",false,"NCT06962059","Healthy Volunteers Study","Vaginal Metabolome Healthy Volunteers Study","Inclusion Criteria:\n\n* has ovaries\n\nExclusion Criteria:\n\n* genetic mutations which increase risk of ovarian cancer: BRCA1\u002F2, BRIP1, PALB2, Lynch Syndrome (MLH1, MSH2\u002FEPCAM, MSH6) and ATM\n* no genetic testing results or unknown genetic status\n* prior cancer diagnosis\n* prior cancer treatment\n* HRT use\n* Antibiotic use (1 month prior to providing sample)",true,"FEMALE","30 Years","50 Years",{"count":68,"type":69},50,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will be collected from healthy volunteers, or those without a known ovarian cancer diagnosis or genetic ovarian cancer risk. These samples will be compared to samples from participants with increased cancer risk and ovarian cancer diagnoses.",[73,74],"Ovarian Cancer","Genetic Predisposition to Disease",[76,77],"vaginal metabolome","ovarian cancer","2026-02-03",{"date":80,"type":81},"2026-02-05","ACTUAL",{"date":83,"type":81},"2025-04-21",{"date":85,"type":69},"2027-05-25",{"name":5,"class":6},1]