[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639524":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":27,"centralContacts":34,"locations":40,"responsibleParty":55,"collaborators":10,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":10,"maxAge":67,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":10,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University","OTHER",[8,12,15,18,21,24],{"label":9,"type":10,"description":11,"interventionNames":10},"HA",null,"Participants suitable for unilateral or bilateral hearing aid(s) fitting, without any other intervention methods (cochlear implantation, gene therapy treatment, auditory brainstem implantation, etc.).",{"label":13,"type":10,"description":14,"interventionNames":10},"CI","Participants suitable for unilateral or bilateral cochlear implantation, without gene therapy treatment or auditory brainstem implantation.",{"label":16,"type":10,"description":17,"interventionNames":10},"ABI","Participants suitable for unilateral or bilateral auditory brainstem implantation.",{"label":19,"type":10,"description":20,"interventionNames":10},"GT","Participants suitable for gene therapy treatment.",{"label":22,"type":10,"description":23,"interventionNames":10},"FU","Participants with hearing loss who do not receive any intervention.",{"label":25,"type":10,"description":26,"interventionNames":10},"NH Control","Participants with normal hearing who are enrolled as healthy controls.",[28,32],{"name":29,"affiliation":30,"role":31},"Hao Wu","Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":33},"STUDY_CHAIR",[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Yun Li","CONTACT","+86-21-53314064","liyuncmm@126.com",[41],{"facility":30,"status":42,"city":43,"state":10,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Shanghai","200011","China","CN",{"type":48,"coordinates":49},"Point",[50,51],121.45806,31.22222,{"lat":51,"lon":50},[54],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},{"type":56,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100639524","hearing-and-brain-development-cohort-in-children-and-adolescents-100639524",false,"NCT07625462","Hearing and Brain Development Cohort in Children and Adolescents","A Longitudinal Cohort Study of Hearing and Brain Development in Children and Adolescents With Hearing Loss Across Different Hearing Management Pathways and in Normal-Hearing Controls","HBD-Cohort","Inclusion Criteria:\n\n* Age no more than 18 years.\n* For the HA\u002FCI\u002FABI\u002FGT\u002FFU groups: behavioral or pure-tone hearing threshold \\>=20 dB HL, or air-conduction ABR \\>=35 dB nHL; For the normal-hearing control group: participants diagnosed as normal hearing by experienced physicians.\n\nExclusion Criteria:\n\n* Inability to cooperate with study testing procedures.",true,"ALL","18 Years",{"count":69,"type":70},5000,"ESTIMATED","OBSERVATIONAL","This bidirectional observational cohort study aims to establish a Hearing and Brain Development (HBD) cohort in children and adolescents with hearing loss across different hearing management pathways, including hearing aid fitting, cochlear implantation, auditory brainstem implantation, gene therapy, and follow-up without intervention, as well as in a normal-hearing control group. Participants will undergo longitudinal assessments of hearing, speech, language, neurodevelopment, and multimodal brain function.",[74],"Hearing Loss","2026-06-03",{"date":77,"type":78},"2026-06-04","ACTUAL",{"date":80,"type":70},"2026-05-20",{"date":82,"type":70},"2030-12-31",{"name":5,"class":6},1]