[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621808":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":40,"centralContacts":47,"locations":53,"responsibleParty":94,"collaborators":96,"id":99,"slug":100,"hasResults":101,"nctId":102,"briefTitle":103,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":101,"sex":106,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":10,"studyType":112,"phases":10,"briefSummary":113,"conditions":114,"keywords":117,"overallStatus":55,"whyStopped":10,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"National Medical Research Center for Therapy and Preventive Medicine","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Сhronic Obstructive Pulmonary Disease",null,"Patients hospitalized with a verified diagnosis of COPD. Patients with a confirmed diagnosis in accordance with instrumental and clinical criteria.",[13,14,15,16,17],"Diagnostic Test: Echocardiography","Diagnostic Test: Spirometry","Diagnostic Test: Body plethysmography","Diagnostic Test: 6-Minute Walk Test (6MWT)","Diagnostic Test: laboratory biomarker analysis",[19,24,28,32,36],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","Echocardiography","Transthoracic echocardiography at rest: with determination of epicardial fat tissue thickness, epicardial adipose tissue thickness (EAT), E\u002Fe', interventricular septum thickness, left ventricular posterior wall thickness, and end-diastolic dimension",[9],{"type":20,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Spirometry","Spirometry is the most common of the pulmonary function tests, which measures the lung capacity and airway patency (volume and speed of air) during quiet and forced breathing.",[9],{"type":20,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"Body plethysmography","Body plethysmography is a non-invasive lung function test performed in a sealed booth (body box) that measures total lung volume, functional residual capacity, and airway resistance by using Boyle's Law to track pressure and volume changes as a patient breathes, providing crucial data for diagnosing conditions like COPD and asthma, and differentiating them from other lung disorders",[9],{"type":20,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"6-Minute Walk Test (6MWT)","The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity",[9],{"type":20,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"laboratory biomarker analysis","Routine and special laboratory tests",[9],[41,44],{"name":42,"affiliation":5,"role":43},"Olga D Dzhioeva, MD, associate professor","STUDY_DIRECTOR",{"name":45,"affiliation":46,"role":43},"Diana I Abdulganieva, MD, professor","Kazan State Medical University",[48],{"name":49,"role":50,"phone":51,"phoneExt":10,"email":52},"Yury S Timofeev, PhD","CONTACT","+79150104788","Timofeev_lab@mail.ru",[54,76],{"facility":46,"status":55,"city":56,"state":10,"zip":10,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"RECRUITING","Kazan'","Russia","RU",{"type":60,"coordinates":61},"Point",[62,63],49.12214,55.78874,{"lat":63,"lon":62},[66,69,72,74],{"name":45,"role":50,"phone":67,"phoneExt":10,"email":68},"+78432360922","diana.abdulganieva@kazangmu.ru",{"name":70,"role":71,"phone":10,"phoneExt":10,"email":10},"Elina R Kirillova, PhD, Associate Professor","SUB_INVESTIGATOR",{"name":73,"role":71,"phone":10,"phoneExt":10,"email":10},"Nailya G Shamsutdinova, PhD, Associate Professor",{"name":45,"role":75,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"facility":5,"status":55,"city":77,"state":10,"zip":10,"country":57,"countryCode":58,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Moscow",{"type":60,"coordinates":79},[80,81],37.61781,55.75204,{"lat":81,"lon":80},[84,88,90,92],{"name":85,"role":50,"phone":86,"phoneExt":10,"email":87},"Olga N. Dzhioeva, MD, Associate Professor","+79166141821","odzhioeva@gnicpm.ru",{"name":89,"role":71,"phone":10,"phoneExt":10,"email":10},"Yriy S Timofeev, PhD",{"name":91,"role":71,"phone":10,"phoneExt":10,"email":10},"Elizaveta A. Rogozhkina, PhD",{"name":93,"role":75,"phone":10,"phoneExt":10,"email":10},"Olga N Dzhioeva, PhD, Associate Professor",{"type":95,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[97],{"name":46,"class":98},"OTHER","100621808","heart-failure-with-preserved-ejection-fraction-in-patients-with-hronic-obstructive-pulmonary-disease-clinical-course-and-prognosis-100621808",false,"NCT07375433","Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinical Course and Prognosis","HIPSTER","Inclusion Criteria:\n\n1. Verified diagnosis of COPD;\n2. Patients hospitalized with COPD;\n3. Citizenship of the Russian Federation;\n4. Patients aged 50 to 70 years;\n5. Patient consent to participate in the study.\n\nExclusion Criteria:\n\n1. Lack of Russian Federaion citizenship;\n2. Patient's refusal to participate in the study;\n3. Any chronic diseases, other than COPD, that affect the prognosis, in the acute and\u002For decompensated stage;\n4. Mental disorders.","ALL","50 Years","70 Years",{"count":110,"type":111},200,"ESTIMATED","OBSERVATIONAL","Study aim is comparison of heart failire with preserved ejection fraction (HFpEF) detection rate in patients with Сhronic Obstructive Pulmonary Disease (COPD) and the clinical course and prognosis in patients with COPD depending on HFpEF presence.",[115,116],"COPD (Chronic Obstructive Pulmonary Disease)","Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)",[118,119,120,121,122],"Heart failure","Heart failure with Preserved Ejection Fraction","Biomarkers","COPD","Prognosis","2026-02-07",{"date":125,"type":126},"2026-02-10","ACTUAL",{"date":128,"type":126},"2026-01-01",{"date":130,"type":111},"2026-12-31",{"name":5,"class":6},2]