[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602849":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":59,"collaborators":23,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":23,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":23,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":23,"overallStatus":41,"whyStopped":23,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Heavy-Load Resistance Training with Blood Flow Restriction","EXPERIMENTAL","In this group, the participants will perform three important exercises namely back squats, leg press, and bench press. Those exercises were performed at a training intensity ranging from 70-80% of each person's 1-repetition maximum (1RM). 12 cm pneumatic cuffs was placed proximally on the thigh (for exercise of lower body) and arm (for exercise of upper body), and blood flow restriction was applied through them. Doppler ultrasound was used weekly to measure limb occlusion pressure (LOP) to then set the cuff pressure at 50% of each participant's predetermined LOP. During working sets it was made the cuffs inflated but during rest periods they were deflated. The exercise protocol consists of:",[13],"Other: Heavy-Load Resistance Training with Blood Flow Restriction",{"label":15,"type":10,"description":16,"interventionNames":17},"Heavy-Load Resistance Training Only (HLRT)","This control group will perform the identical exercise protocol (same exercises, intensities, volumes, and rest periods) as the BFR group, but without any blood flow restriction application. The same progression criteria will be used for both groups to ensure comparable training stimulus.",[18],"Other: Heavy-Load Resistance Training Only",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"Blood Flow Restriction (BFR) Training (also known as \"Kaatsu\" training is an innovative and increasingly popular exercise technique to improve muscle strength and hypertrophy with relatively low loads. Heavy Load Resistance Training (HL-RT) is one of the most effective exercise methodology that is widely used to increase muscular strength and hypertrophy.",[9],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Heavy-Load Resistance Training Only","Heavy Load Resistance Training (HL-RT) is one of the most effective exercise methodology that is widely used to increase muscular strength and hypertrophy.",[15],[29],{"name":30,"affiliation":5,"role":31},"Muhammad Hassan, MSPT","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":23,"email":37},"Imran Amjad, Phd PT","CONTACT","03324390125","imran.amjad@riphah.edu.pk",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Pakistan Sports Board","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":48,"coordinates":49},"Point",[50,51],74.35071,31.558,{"lat":51,"lon":50},[54,57],{"name":55,"role":35,"phone":56,"phoneExt":23,"email":23},"Hafiz Amir","04299230383",{"name":58,"role":31,"phone":23,"phoneExt":23,"email":23},"Mubashra Waheed, DPT",{"type":60,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100602849","heavy-load-resistance-training-with-and-without-blood-flow-restriction-therapy-in-athletes-100602849",false,"NCT07128862","Heavy-load Resistance Training With and Without Blood Flow Restriction Therapy in Athletes","Effects of Heavy-load Resistance Training With and Without Blood Flow Restriction Therapy on Quadriceps Muscle Strength and Endurance in Athletes","Inclusion Criteria:\n\n* Participants with age between 18 and 35 years.\n* Active individual participating in sport activities at least 3 times a week for the past 6 months.\n* Participants with any non-heart conditions.\n* Individuals voluntarily participating and providing informed consent.\n* Sprinters, Footballer\n\nExclusion Criteria:\n\n* Individuals with DVT or other pulmonary artery disease.\n* Pregnant women or those planning to become pregnant.\n* Participants with recent musculoskeletal injuries (within the 6 months).\n* Individuals currently involved in another study.\n* Participants allergic to or sensitive to the materials used in the BFR bands.\n* Individuals who anticipate being unable to attend all training sessions.",true,"ALL","18 Years","35 Years",{"count":73,"type":74},44,"ESTIMATED","INTERVENTIONAL",[77],"NA","A 8 weeks, single-blinded randomized controlled trial will be conducted at Pakistan Sports Board (PSB). Forty-four athletes (18-35 years) will be randomized into Group A (HL-RT + BFR, n = 22) and Group B (HL-RT only, n = 22). BFR will be applied at 50% limb occlusion pressure during lower-body exercises (squats, leg press). Both groups trained 3x\u002Fweek for 4 weeks at 70-80% 1RM. Outcomes included 1RM strength, squat endurance, push-up performance, and International Physical Activity Questionnaire (IPAQ) scores.",[80],"Sports Physical Therapy","2025-08-18",{"date":83,"type":84},"2025-08-19","ACTUAL",{"date":86,"type":84},"2024-07-30",{"date":88,"type":74},"2025-09-02",{"name":5,"class":6},1]