[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586093":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":109,"collaborators":18,"id":111,"slug":112,"hasResults":113,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":113,"sex":118,"minAge":119,"maxAge":18,"enrollmentInfo":120,"targetDuration":18,"studyType":123,"phases":124,"briefSummary":126,"conditions":127,"keywords":131,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":147},{"fullName":5,"class":6},"University Hospital, Limoges","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention arm","EXPERIMENTAL","As soon as an eligible patient is identified by the nurse, in addition to the classic hemodynamic parameters measured in all patients, a measurement of the peripheral perfusion index (from 1 sec to 10 sec) and marbling assessment (scale from 0 to 5) will be performed. This measurement will be validated by the senior doctor of the Sepsis Department. When the peripheral perfusion index will be ≥ 3 sec and\u002For the marbling score ≥ 1, a first vascular filling test of 500 cc over 30 minutes will be started, regardless of the value of the hemodynamic parameters.",[13],"Diagnostic Test: measurement of the peripheral perfusion index and marbling assessment",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","NO_INTERVENTION","Patients will benefit from treatment according to current standards of care",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","measurement of the peripheral perfusion index and marbling assessment","in addition to the classic hemodynamic parameters measured in all patients, a measurement of the peripheral perfusion index (from 1 sec to 10 sec) and marbling assessment (scale from 0 to 5) will be performed",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Anaelle NARDOT-SUCHAUD","CONTACT","0519761835","Anaelle.NARDOT-SUCHAUD@chu-limoges.fr",[32,49,61,73,85,97],{"facility":33,"status":34,"city":35,"state":18,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Brive Hospital","RECRUITING","Brivé","19100","France","FR",{"type":40,"coordinates":41},"Point",[42,43],-2.00321,47.48857,{"lat":43,"lon":42},[46],{"name":47,"role":48,"phone":18,"phoneExt":18,"email":18},"Pierrick BARDOU","PRINCIPAL_INVESTIGATOR",{"facility":50,"status":34,"city":51,"state":18,"zip":52,"country":37,"countryCode":38,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Guéret Hospital","Guéret","23000",{"type":40,"coordinates":54},[55,56],1.87166,46.17185,{"lat":56,"lon":55},[59],{"name":60,"role":48,"phone":18,"phoneExt":18,"email":18},"Amaury GALAUD",{"facility":62,"status":34,"city":63,"state":18,"zip":64,"country":37,"countryCode":38,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Limoges University Hospital","Limoges","87000",{"type":40,"coordinates":66},[67,68],1.24759,45.83362,{"lat":68,"lon":67},[71],{"name":72,"role":48,"phone":18,"phoneExt":18,"email":18},"Manon DUMOLARD",{"facility":74,"status":34,"city":75,"state":18,"zip":76,"country":37,"countryCode":38,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Saint Junien Hospital","Saint-Junien","87200",{"type":40,"coordinates":78},[79,80],0.90158,45.88746,{"lat":80,"lon":79},[83],{"name":84,"role":48,"phone":18,"phoneExt":18,"email":18},"Morgan GAURIAT",{"facility":86,"status":34,"city":87,"state":18,"zip":88,"country":37,"countryCode":38,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Tulle Hospital","Tulle","19012",{"type":40,"coordinates":90},[91,92],1.77233,45.26582,{"lat":92,"lon":91},[95],{"name":96,"role":48,"phone":18,"phoneExt":18,"email":18},"Philippe DUPUY",{"facility":98,"status":34,"city":99,"state":18,"zip":100,"country":37,"countryCode":38,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Ussel Hospital","Ussel","19200",{"type":40,"coordinates":102},[103,104],2.30917,45.54804,{"lat":104,"lon":103},[107],{"name":108,"role":48,"phone":18,"phoneExt":18,"email":18},"Cyril MOESCH",{"type":110,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100586093","hemodynamic-evaluation-using-microcirculation-for-early-treatment-of-septic-patients-100586093",false,"NCT06910891","Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients","HEMOCAP","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Admitted to the Emergency Department for suspected Sepsis for less than 6 hours according to international Sepsis-3 definitions (high probability of infection defined by a fever greater than or equal tol to 38.3°C with a suspected infectious source + Score NEWS 2 greater than or equal to 2)\n3. Affiliated to a social security system\n4. Having agreed to participate in this study\n\nExclusion Criteria:\n\n1. Patient with arterial hypotension (SBP ≤ 100 mmHg) on admission\n2. Patient having already received a 500mL filling test over 30 minutes\n3. Patients moribund according to the investigator\n4. Pregnancy or breastfeeding\n5. Patient under guardianship, curatorship or safeguard of justice","ALL","18 Years",{"count":121,"type":122},556,"ESTIMATED","INTERVENTIONAL",[125],"NA","Despite early treatment, the deterioration and mortality of sepsis patients remains high. A possible explanation could be persistent tissue hypoperfusion, or undetected in the early phase despite the normalization of macro-hemodynamic parameters. This interventional study evaluates the impact of measuring microcirculation parameters by nurses on patient prognosis through early initiation of vascular filling.",[128,129,130],"Sepsis","Emergency Care","Microcirculation",[132,133,134,135,136,137],"microcirculation","septic patient","organ dysfunction","sepsis","peripheral perfusion index","emergency unit","2025-11-18",{"date":140,"type":141},"2025-11-21","ACTUAL",{"date":143,"type":141},"2025-09-20",{"date":145,"type":122},"2027-03-28",{"name":5,"class":6},6]