[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100331210":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":22,"responsibleParty":40,"collaborators":7,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":7,"studyType":56,"phases":7,"briefSummary":57,"conditions":58,"keywords":7,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Yale University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Lower body negative pressure","We will be monitoring the changes in central and peripheral monitors\u002Fwaveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.",[14],{"name":15,"affiliation":5,"role":16},"Aymen Alian, MD","PRINCIPAL_INVESTIGATOR",[18],{"name":15,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","203-785-2802","aymen.alian@yale.edu",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"John B. Pierce Laboratory","RECRUITING","New Haven","Connecticut","06520","United States","US",{"type":32,"coordinates":33},"Point",[34,35],-72.92816,41.30815,{"lat":35,"lon":34},[38],{"name":39,"role":19,"phone":20,"phoneExt":7,"email":21},"Aymen A Alian",{"type":41,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100331210","hemodynamics-monitoring-during-lower-body-negative-pressure-lbnp-induced-controlled-hypovolemia-100331210",false,"NCT03592290","Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia","LBPN","Inclusion Criteria:\n\n\\* Healthy volunteers aged 20-45 with\n\nExclusion Criteria:\n\n* Pregnant women\n* Under 20 years of age\n* Subjects with coronary artery disease, diabetes, epilepsy and hypertension",true,"ALL","20 Years","45 Years",{"count":54,"type":55},120,"ESTIMATED","OBSERVATIONAL","To monitor the changes in central and peripheral monitors\u002Fwaveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.",[59,60],"Hypovolemia","Hemodynamic Instability","2026-01-15",{"date":63,"type":64},"2026-01-20","ACTUAL",{"date":66,"type":64},"2017-11-15",{"date":68,"type":55},"2027-01",{"name":5,"class":6},1]