[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100442670":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":56,"collaborators":58,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":26,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":26,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Hospital Clinic of Barcelona","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Conventional treatment","ACTIVE_COMPARATOR","Patients receiving conventional treatment for multiorganic dysfunction syndrome from septic origin.",[13],"Procedure: Conventional treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Extracorporeal support with haemoperfusion treatment","EXPERIMENTAL","Patients receiving extracorporeal support with haemoperfusion for multiorganic dysfunction syndrome from septic origin.",[19],"Procedure: Extracorporeal support with haemoperfusion",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Extracorporeal support with haemoperfusion","Use of extracorporeal support with haemoperfusion",[15],null,{"type":22,"name":9,"description":9,"armGroupLabels":28,"otherNames":26},[9],[30],{"name":31,"affiliation":32,"role":33},"Fernando Sanchez Moran","Hospital General Universitario de Castellon","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Fernando Sánchez Morán","CONTACT","964399914","sanchez_fermor@gva.es",[41],{"facility":32,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Castellon","Castellón","12004","Spain","ES",{"type":49,"coordinates":50},"Point",[51,52],-0.04935,39.98567,{"lat":52,"lon":51},[55],{"name":31,"role":37,"phone":26,"phoneExt":26,"email":39},{"type":57,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[59,61,63,65],{"name":60,"class":6},"Hospital General Universitario de Castellón",{"name":62,"class":6},"Hospital Universitario La Paz",{"name":64,"class":6},"Hospital de Granollers",{"name":66,"class":6},"Hospital General Universitario Santa Lucía","100442670","hemoperfusion-in-critical-patients-with-septic-multiorgan-dysfunction-syndrome-100442670",false,"NCT05044403","Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome.","Clinical Impact of Hemoperfusion With a Neutral Macroporous Resin Cartridge as Adjunctive Treatment in Septic Patients With Multiorgan Dysfunction Syndrome (MODS) Admitted to Intensive Care Units.","Inclusion Criteria:\n\n* Patients with a sepsis diagnosis, according to the diagnostic criteria of the International Sepsis-3 Consensus Conference, and without response to the treatment of septic shock who meet the following conditions:\n* Sepsis of abdominal origin with controlled infectious focus.\n* Noradrenaline dose\\> 0.5 µg \u002F kg \u002F min to maintain adequate organ perfusion after optimization of fluid therapy.\n* Dysfunction of two or more organs with SOFA ≥ 9 (5).\n* Blood lactate ≥ 2 mmol \u002F L.\n* Procalcitonin (PCT)\\> 10 ng \u002F mL.\n* CRP\\> 100 mg \u002F L.\n* IL-6\\> 2000 pg \u002F ml.\n\nExclusion Criteria:\n\n* Age under 18 years or over 80 years.\n* Pregnancy or breastfeeding.\n* Terminally ill patients or with a life expectancy of less than 48 hours.\n* Thrombocytopenia \\\u003C60,000 \u002F mm3.\n* Pancytopenia.\n* Severe coagulopathy with high risk of bleeding.\n* Inclusion in another research protocol.\n* In case of re-entry during the study period, only the first admission will be included.\n* Use of another haemoperfusion device.","ALL","18 Years","80 Years",{"count":78,"type":79},48,"ESTIMATED","INTERVENTIONAL",[82],"NA","Low-level interventional clinical trial to evaluate the effectiveness and safety of extracorporeal support with hemoperfusion in critical patients with septic multiorgan dysfunction syndrome.",[85,86,87],"Hemoperfusion","Multiorgan Failure","Sepsis","2025-06-04",{"date":90,"type":91},"2025-06-10","ACTUAL",{"date":93,"type":91},"2023-03-01",{"date":95,"type":79},"2025-12-20",{"name":5,"class":6},1]