[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100202604":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":26,"responsibleParty":57,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Ulm","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"patients with cytopenias",null,"Patients with sepsis and concomitant cytopenias (leukopenia with thrombocytopenia and anemia) who are routinely treated with rhG-CSF will be followed for reconstitution of peripheral blood cell counts. In cooperation with the Department of Hematology, patients are examined for bone marrow cellularity and hemophagocytosis if G-CSF treatment does not result in leukocyte increase.",[13],{"name":14,"affiliation":15,"role":16},"Manfred E Weiss, MD","Department of Anesthesiology","PRINCIPAL_INVESTIGATOR",[18,22],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","49-731-50060226","manfred.weiss@uniklinik-ulm.de",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},"Elisabeth M Schneider, PhD","49-731-50060080","marion.schneider@uni-ulm.de",[27,45],{"facility":28,"status":29,"city":30,"state":10,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Department of Anaesthesiology, University Hospital Ulm","RECRUITING","Ulm","89075","Germany","DE",{"type":35,"coordinates":36},"Point",[37,38],9.99155,48.39841,{"lat":38,"lon":37},[41,43],{"name":14,"role":19,"phone":42,"phoneExt":10,"email":21},"49 (0)731-500-60226",{"name":23,"role":19,"phone":44,"phoneExt":10,"email":25},"49 (0)731-500-60319",{"facility":46,"status":29,"city":30,"state":10,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":47,"geoPoint":49,"contacts":50},"Department of Internal Medicine III, Comprehensive Infectious Disease Center, University Hospital Ulm, Germany",{"type":35,"coordinates":48},[37,38],{"lat":38,"lon":37},[51,55],{"name":52,"role":19,"phone":53,"phoneExt":10,"email":54},"Martin Bommer, MD","+49 (731) 500-45530","Martin.Bommer@uniklinik-ulm.de",{"name":23,"role":19,"phone":56,"phoneExt":10,"email":25},"+49 (731) 500-60080",{"type":16,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Manfred Weiss","Professor, MD, MBA","100202604","hemophagocytosis-in-critically-ill-adult-patients-100202604",false,"NCT01913938","Hemophagocytosis in Critically Ill Adult Patients","Hemophagocytosis in Critically Ill Adult Patients With Cytopenias","HCIAP","Inclusion Criteria:\n\n* age \\> 18 years\n* critically ill adult patients\n* leukopenia and thrombocytopenia\n* rhG-CSF therapy\n\nExclusion Criteria:\n\n* life expectancy \\\u003C 24 hours\n* inclusion in other studies\n* trauma patients with reanimation on scene or immediately dying on hospital admission\n* pregnancy\n* hematologic disorder, malignancy\n* high dose corticosteroid treatment or chemotherapy","ALL","18 Years","90 Years",{"count":72,"type":73},40,"ESTIMATED","OBSERVATIONAL","The purpose of the study is to find out whether non-responsiveness to therapeutic recombinant human granulocyte colony-stimulation factor (rhG-CSF) is associated with hemophagocytosis in critically ill adult patients with cytopenias.",[77],"Hemophagocytosis",[79],"Hemophagocytosis, adults, rhG-CSF","2024-01-16",{"date":82,"type":83},"2024-01-17","ACTUAL",{"date":85,"type":10},"2013-07",{"date":87,"type":73},"2026-12",{"name":5,"class":6},2]