[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604346":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":41,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"Edwards Lifesciences","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Primary Cohort (Swan)",null,"Up to 100 subjects with planned monitoring with a pulmonary artery catheter in the OR.",[13],"Device: HemoSphere Alta Monitor, Swan-Ganz IQ pulmonary arterial catheter, ForeSight IQ Large sensor, and Acumen IQ sensor",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","HemoSphere Alta Monitor, Swan-Ganz IQ pulmonary arterial catheter, ForeSight IQ Large sensor, and Acumen IQ sensor","Subjects with planned monitoring with a pulmonary artery catheter in the operating room, will be monitored with the above listed devices.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Cristina Johnson","CONTACT","949-308-5850","apmhsalta.study@bd.com",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":10},"University of Rochester Medical Center","RECRUITING","Rochester","New York","14620","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-77.61556,43.15478,{"lat":39,"lon":38},{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100604346","hemosphere-alta-study-100604346",false,"NCT07148323","HemoSphere Alta Study","HemoSphere Alta Clinical Development Study","Inclusion Criteria:\n\n1. Signed informed consent\n2. Age ≥ 18 years\n3. Planned monitoring with a pulmonary artery catheter\n4. Patient scheduled to undergo cardiac or liver transplant surgery lasting \\> 2 hours\n5. Additional criteria for Sub-Cohort A (RVF)\n\n   1. Possible Right Ventricular Dysfunction\u002FFailure based on pre-operative assessment of previous Transthoracic Echocardiogram (TTE)\n   2. Planned Transesophageal Echocardiogram (TEE) assessment during the operative procedure\n6. Additional criteria for Sub-Cohort B (CAI)\n\n   1. Age ≥ 45 years\n   2. Planned cardiac surgery with Cardiopulmonary Bypass (CPB)\n   3. Ability to place ForeSight IQ and Acumen IQ sensors during the operative monitoring period\n   4. High risk for cerebral vascular disease, defined as: a history of hypertension, pulse pressure \\> 60 mmHg, diabetes, stroke, transient ischemic attack, carotid bruit, tobacco smoking, or peripheral vascular disease\n\nExclusion Criteria:\n\n1. Inability to provide informed consent\n2. Pregnancy as confirmed per EMR\n3. Patients deemed not suitable for the study at the discretion of the Investigator\n4. Participation in another study that clinically interferes with the current study\n5. Additional exclusion criteria for Sub-Cohort A\n\n   1. Presence of left bundle branch block\n   2. Presence of current\u002Frecurrent sepsis\n   3. Presence of hypercoagulability, as identified in the patient's past medical history and preoperative evaluation\n   4. Structural abnormality, including congenital heart defects, of the right ventricle\n6. Additional exclusion criteria for Sub-Cohort B a. Surgery for congenital heart defect","ALL","18 Years",{"count":53,"type":54},100,"ESTIMATED","OBSERVATIONAL","A prospective, non-randomized single arm study using the HemoSphere Alta Advanced Monitoring Platform and associated devices in adult subjects. Data collected from enrolled study subjects will be used for continual device development purposes.",[58],"Hemodynamic Instability","2025-11-06",{"date":61,"type":62},"2025-11-10","ACTUAL",{"date":64,"type":62},"2025-10-14",{"date":66,"type":54},"2026-12",{"name":5,"class":6},1]