[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100363125":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":52,"collaborators":56,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Swiss Federal Institute of Technology","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High Iron Group","ACTIVE_COMPARATOR","15 women taking 100 mg iron twice daily for 4 days (800 mg).",[13],"Dietary Supplement: 100mg iron fumarate",{"label":15,"type":10,"description":16,"interventionNames":17},"Low Iron Group","15 women taking 30 mg iron once daily for 14 days (420 mg).",[18],"Dietary Supplement: Burgerstein Schwangerschaft & Stillzeit",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","100mg iron fumarate","100mg iron fumarate b.i.d. for 4 consecutive days",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Burgerstein Schwangerschaft & Stillzeit","contains 30 mg iron fumarate, given on 14 consecutive days",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Nicole U Stoffel, PhD","CONTACT","+41 44 632 83 93","nicole.stoffel@hest.ethz.ch",[37],{"facility":38,"status":39,"city":40,"state":25,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Human Nutrition Laboratory ETH Zurich","RECRUITING","Zurich","8092","Switzerland","CH",{"type":45,"coordinates":46},"Point",[47,48],8.55,47.36667,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Isabelle Herter-Aeberli","PhD",[57],{"name":58,"class":6},"University Hospital, Zürich","100363125","hepcidin-and-glucose-metabolism-100363125",false,"NCT04008147","Hepcidin and Glucose Metabolism","The Effect of Oral Iron Supplements on Hepcidin, Insulin and Glucose Metabolism in Pregnancy","Inclusion Criteria:\n\n* week of pregnancy 24-28\n* pre-pregnancy BMI \\\u003C27.5kg\u002Fm2\n* singleton pregnancy\n* Hb \\> 8.0 g\u002Fdl\n\nWilling to either:\n\n* not take any iron supplements for 14 days (however, participants will receive a similar amount of total iron during the 4 study days that they would normally receive over 14 days) OR\n* to take the multivitamin \"Burgerstein Schwangerschaft and Stillzeit\" supplements over the 14 days (contains 30 mg iron)\n\nExclusion Criteria:\n\n* iron infusion within the past 6 months\n* severely anemic Hb\\\u003C8.0g\u002Fdl\n* acute or chronic disease\n* long-term medication\n* medical problems known to affect iron homeostasis\n* smoking","FEMALE","18 Years","45 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","Gestational diabetes mellitus (GDM), defined as hyperglycemia with blood glucose values above normal but below those diagnostic of DM, and iron deficiency (ID) with or without anemia (IDA) are common during pregnancy. Both disease patterns are associated with an increased risk of complications during pregnancy and at delivery and may have a variety of negative effects on different aspects of child development. Thus, GDM and ID\u002FIDA during pregnancy should be prevented.\n\nWhether iron supplementation with high oral doses acutely increases hepcidin during pregnancy, and whether this acute iron-induced increase in hepcidin decreases insulin sensitivity, is uncertain.",[77,78,79,80],"Iron Deficiency Anemia of Pregnancy","Iron Metabolism Disorders","Glucose Intolerance","Gestational Diabetes","2025-05-19",{"date":83,"type":84},"2025-05-22","ACTUAL",{"date":86,"type":84},"2019-07-03",{"date":88,"type":71},"2025-12-31",{"name":5,"class":6},1]