[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100324415":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":29,"locations":37,"responsibleParty":55,"collaborators":20,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":20,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":20,"enrollmentInfo":66,"targetDuration":20,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":20,"overallStatus":75,"whyStopped":20,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Composite Interceptive Med Science","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","All the eligible participants will receive Livitol-17 capsules. It consist of 390 mg of whole herbs and extract of Phyllanthus niruri (Bhumyamalaki), Boerhaavia diffusa (Punarnava) and Picroorrhiza kurroa (Katuki).",[13],"Drug: Livitol-70",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","Livitol-70","Livitol-17 detoxifies, purifies and rejuvenates liver, kidney and spleen. Participants will be given the intervention in two bottles at each visit. Participant will be instructed to take two capsule twice daily at a fixed time in the day.",[9],null,[22,26],{"name":23,"affiliation":24,"role":25},"Alben Sigamani, MD","Narayana Hrudayalaya Hospital","PRINCIPAL_INVESTIGATOR",{"name":27,"affiliation":5,"role":28},"Sanjaya Chauhan, PharmD","STUDY_CHAIR",[30,34],{"name":23,"role":31,"phone":32,"phoneExt":20,"email":33},"CONTACT","8884431444","alben.sigamani.dr@narayanahealth.org",{"name":27,"role":31,"phone":35,"phoneExt":20,"email":36},"9611252350","drsanjayachauhan49@gmail.com",[38],{"facility":39,"status":20,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Mazumdar Shaw Medical Centre","Bangalore","Karnataka","560099","India","IN",{"type":46,"coordinates":47},"Point",[48,49],77.59369,12.97194,{"lat":49,"lon":48},[52,53],{"name":23,"role":31,"phone":32,"phoneExt":20,"email":33},{"name":27,"role":31,"phone":35,"phoneExt":54,"email":36},"Chauhan",{"type":56,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100324415","herbal-supplements-for-improvement-of-liver-function-in-participants-with-alcoholic-liver-disease-100324415",false,"NCT03503708","Herbal Supplements for Improvement of Liver Function in Participants With Alcoholic Liver Disease","Antioxidant for Improvement of Hepatic Function in Patients With Alcohol Liver Disease Without Cirrhosis: Non-randomized Interventional Cohort Study","Inclusion Criteria:\n\nAdults aged over 18 years with the evidence of alcoholic liver disease (ALD) based on a thorough history, physical examination, and laboratory tests and all of the following:\n\n* Chronic alcohol intake, Identified with AUDIT(Alcohol Use Disorder Inventory Test) Questionnaire\n* Active alcohol use until 4 weeks prior to presentation\n* ALT and AST elevated \\>1.5 times the upper limit of normal\n* Over 1.5 ratio of AST to ALT\n* Maddrey Discriminant function(DF) less than 30\n\nExclusion Criteria:\n\n* Severe alcoholic hepatitis with cirrhosis or life expectancy less than 3 months\n* Severe renal impairment (Glomerular filtration rate below 60 ml\u002Fmin per 1.73m2)\n* Hepatic disorders due to cardiac causes, inherited metabolic causes, hemochromatosis and Wilson's disease\n* Participants with active viral hepatitis\n* Under going active treatment for alcohol withdrawal syndrome(AWS) at the study entry\n* Participants on hepatotoxic medications like antitubercular medication, antiviral medication, paracetamol etc.\n* Pregnant, attempting to conceive, or lactating women\n* Participating in another clinical trial with an active intervention or drug or device with last dose taken within 60 days.","ALL","18 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","Alcoholic liver disease represents the major health issues and it ranges from simple steatosis to cirrhosis. There is a paucity of data to support the allopathic intervention among these group of patients. Livitol-17 consist of the 3 whole herbs and extract which has antioxidant, hepatoprotective as well as reno-protective properties. The aim of this trial is to study the efficacy of herbal supplement to improve the liver function of alcoholic liver disease subject.",[74],"Alcoholic Liver Disease","NOT_YET_RECRUITING","2018-04-19",{"date":78,"type":79},"2018-04-20","ACTUAL",{"date":81,"type":68},"2018-05-30",{"date":83,"type":68},"2028-11-30",{"name":5,"class":6},1]