[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641633":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":31,"collaborators":26,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":26,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":42,"enrollmentInfo":43,"targetDuration":26,"studyType":46,"phases":47,"briefSummary":49,"conditions":50,"keywords":26,"overallStatus":56,"whyStopped":26,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":26},{"fullName":5,"class":6},"Chung Shan Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High-frequency rTMS + balance training","EXPERIMENTAL","Frequency: 10 Hz; Intensity: 90% RMT; Duration: 4 seconds; Rest time: 26 seconds; Sets: 25; Number of pulses: 1000\\*2; Total time: 25 minutes Followed by an improved Otago exercise program (60 minutes)",[13],"Device: high-frequency repetitive transcranial magnetic stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham rTMS + balance training","SHAM_COMPARATOR","The stimulation parameters were the same as those of the experimental group, with only the stimulation coil rotated 90° to minimize the neurophysiological effects.\n\nFollowed by an improved Otago exercise program (60 minutes)",[19],"Device: Sham rTMS",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","high-frequency repetitive transcranial magnetic stimulation","A painless, non-invasive, and well-tolerated non-pharmacological treatment method-Repetitive Transcranial Magnetic Stimulation (rTMS)-delivers repeated and systematic magnetic field stimulation to specific brain regions through a stimulation coil placed on the scalp. These repeated magnetic pulses not only alter the excitability of the targeted area but also affect anatomically connected brain regions. The parameters are as follows: Frequency: 10 Hz; Intensity: 90% RMT; Duration: 4 seconds; Rest: 26 seconds; Trains: 25 times; Pulses: 1000\\*2; Total time: 25 minutes.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham rTMS","In this study, the sham stimulation group was designed based on previous related research and expert recommendations. Participants in this group will receive 20% of the stimulation intensity used in the treatment group, which is significantly lower than the treatment group's 90%, ensuring a safe and humane experimental design. The parameters are as follows: Frequency: 10 Hz; Intensity: 20% RMT; Duration: 4 seconds; Rest: 26 seconds; Trains: 25 times; Pulses: 1000\\*2; Total time: 25 minutes.",[15],{"type":32,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100641633","hf-rtms-primed-balance-training-on-corticomotor-excitability-balance-and-gait-in-parkinsons-100641633",false,"NCT07653256","HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's","Effects of High-frequency Repetitive Transcranial Magnetic Stimulation-primed Balance Training on Corticomotor Excitability, Balance, and Gait Performance in Parkinson's Disease","Inclusion Criteria:\n\n* Diagnosed with idiopathic PD\n* Aged between 40-80 years\n* Stable on antiparkinsonian medication ( \\> 3 months)\n* H\\&Y I-III\n* Able to walk continuously for at least 10 minutes\n* The ability to follow commands and instructions\n\nExclusion Criteria:\n\n* Neurological diseases other than PD\n* Severe musculoskeletal, cardiopulmonary disorders\n* MMSE \\\u003C 24\n* Contraindications for TMS\n* Have undergone or are scheduled to undergo neurological surgery during the study participation period","ALL","40 Years","80 Years",{"count":44,"type":45},20,"ESTIMATED","INTERVENTIONAL",[48],"NA","This study aims to investigate the effects of repeated transcranial magnetic stimulation combined with modified otago exercise program balance training intervention on motor cortex excitability, balance, and gait performance in patients with Parkinson's disease.",[51,52,53,54,55],"Parkinson's Disease","Corticomotor Excitability","Balance Control","Gait Performance","Motor Symptoms","NOT_YET_RECRUITING","2026-06-11",{"date":59,"type":60},"2026-06-17","ACTUAL",{"date":62,"type":45},"2026-07-01",{"date":64,"type":45},"2028-04-01",{"name":5,"class":6}]