[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502882":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":68,"collaborators":26,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"National Taiwan University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"high flow nasal cannula group","EXPERIMENTAL","All patients will have FiO2 started at 0.4 and titrated to maintain oxygen saturation (SpO2) ≥ 95%. The flow rate will be set at titrated from 60 L\u002Fmin.",[13],"Procedure: high flow nasal cannula",{"label":15,"type":16,"description":17,"interventionNames":18},"Oxygen Mask group","ACTIVE_COMPARATOR","All patients will have FiO2 started at 0.4 and titrated to maintain oxygen saturation (SpO2) ≥ 95%.",[19],"Procedure: Oxygen mask",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","high flow nasal cannula","the patient receives HFNC after randomization. All patients will have FiO2 started at 0.4 and titrated to maintain oxygen saturation (SpO2) ≥ 95%.",[9],null,{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Oxygen mask",[15],[31],{"name":32,"affiliation":33,"role":34},"Hsien-Chi Liao, MD","department of trauma of National University Hospital","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+886-972651611","polarisliao@hotmail.com",[41,53],{"facility":42,"status":43,"city":44,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":26,"geoPoint":26,"contacts":48},"Department of Traumatology, National Taiwain University Hospital","RECRUITING","Taipei","10002","Taiwan","TW",[49],{"name":50,"role":37,"phone":51,"phoneExt":52,"email":39},"Hsien-Chi Liao, M.D.","886-2-23123456","51611",{"facility":54,"status":43,"city":44,"state":46,"zip":55,"country":46,"countryCode":47,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"NTUH Hsin-Chu Branch; NTUH Yun-Lin Branch","100; 300; 640; 280",{"type":57,"coordinates":58},"Point",[59,60],121.52639,25.05306,{"lat":60,"lon":59},[63,67],{"name":64,"role":37,"phone":65,"phoneExt":26,"email":66},"Pei-Hsing Chen, MD","+886-972653530","b96401034@ntu.edu.tw",{"name":64,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":69,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100502882","hfnc-compared-with-facial-mask-in-patients-with-chest-trauma-patients-100502882",false,"NCT05828030","HFNC Compared With Facial Mask in Patients With Chest Trauma Patients","Noninvasive Ventilation With High Flow Nasal Cannula Compared With Facial Mask in Patients With Chest Trauma: a Randomized Controlled Study","Inclusion Criteria:\n\nPatients who have the following condition within 72 hours of chest trauma despite receiving standard nasal cannula oxygen therapy \\[≥10 L\u002Fmin\\], are eligible for inclusion.\n\n* severe hypoxemic respiratory failure \\[Arterial partial pressure of oxygen (PaO2)\u002Ffraction of inspired oxygen fraction(FiO2) \\\u003C300 mmHg\\]\n* with a respiratory rate \\>25 breaths\u002Fminute and difficulty breathing, or respiratory distress\n* PaCO2 of 45 mmHg or higher (if the patient requires emergency surgery with endotracheal intubation and mechanical ventilation, the time of inclusion will be the start of the post-extubation period. (Note: For patients who receive emergency trauma surgery with endotracheal intubation and mechanical ventilation, the time of inclusion assessment will be 72 hours after extubation.)\n\nExclusion Criteria:\n\n1. Patients with a Glasgow Coma Scale less than 8 or severe brain injury.\n2. Patients with any contraindications to non-invasive ventilation, including acute gastrointestinal bleeding, upper airway obstruction, or hemodynamic instability.\n3. Facial trauma involving skull base fractures, facial bone fractures, or orbital floor fractures.\n4. Severe injuries involving the nasal sinuses.\n5. Patients with cervical spine injuries.\n6. Patients with increased intracranial pressure.\n7. Patients with facial, nasal, or airway structural abnormalities or surgery that prevents the use of appropriate nasal cannula.\n8. Patients after upper airway surgery.\n9. Patients who are unable to clearly express their willingness to sign informed consent.","ALL","20 Years","99 Years",{"count":81,"type":82},100,"ESTIMATED","INTERVENTIONAL",[85],"NA","Guidelines for noninvasive ventilation (NIV) recommend continuous positive airway pressure in patients with thoracic trauma who remain hypoxic . However, no any suggestion was applied for high flow nasal cannula (HFNC). Therefore, Our aim was to determine whether HFNC reduces intubation in severe trauma-related hypoxemia.",[88,89],"Chest Trauma","Hypoxia","2025-09-01",{"date":92,"type":93},"2025-09-08","ACTUAL",{"date":95,"type":93},"2023-04-26",{"date":97,"type":82},"2027-12-31",{"name":5,"class":6},2]