[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638571":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":39,"locations":45,"responsibleParty":61,"collaborators":30,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":30,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":30,"enrollmentInfo":75,"targetDuration":30,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":89,"whyStopped":30,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Firat University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"HF40","EXPERIMENTAL","Participants receive high-flow nasal oxygen (HFNO) therapy at a flow rate of 40 L\u002Fmin during procedural sedation for cystoscopy.",[13],"Device: High-Flow Nasal Oxygen 40 L\u002Fmin (HF40)",{"label":15,"type":10,"description":16,"interventionNames":17},"HF55","Participants receive HFNO therapy at a flow rate of 55 L\u002Fmin during procedural sedation for cystoscopy.",[18],"Device: High-Flow Nasal Oxygen 55 L\u002Fmin (HF55)",{"label":20,"type":10,"description":21,"interventionNames":22},"HF70","Participants receive HFNO therapy at a flow rate of 70 L\u002Fmin during procedural sedation for cystoscopy.",[23],"Device: High-Flow Nasal Oxygen 70 L\u002Fmin (HF70)",[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","High-Flow Nasal Oxygen 40 L\u002Fmin (HF40)","Participants receive high-flow nasal oxygen (HFNO) therapy delivered through the OptiFlow™ system at a flow rate of 40 L\u002Fmin with 100% heated and humidified oxygen during procedural sedation for cystoscopy. Sedation is achieved using midazolam, remifentanil, and propofol.",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"High-Flow Nasal Oxygen 55 L\u002Fmin (HF55)","Participants receive HFNO therapy via the OptiFlow™ system at a flow rate of 55 L\u002Fmin with 100% heated and humidified oxygen during procedural sedation for cystoscopy, together with the same standardized sedation protocol.",[15],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"High-Flow Nasal Oxygen 70 L\u002Fmin (HF70)","Participants receive HFNO therapy via the OptiFlow™ system at a flow rate of 70 L\u002Fmin with 100% heated and humidified oxygen during procedural sedation for cystoscopy, together with the same standardized sedation protocol.",[20],[40],{"name":41,"role":42,"phone":43,"phoneExt":30,"email":44},"Ahmet Aksu, Assistant Professor","CONTACT","+905303493896","drahmetaksu@gmail.com",[46],{"facility":47,"status":30,"city":48,"state":49,"zip":50,"country":51,"countryCode":30,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Fırat University Faculty of Medicine Hospital","Elâzığ","Elaziğ","23100","Turkey (Türkiye)",{"type":53,"coordinates":54},"Point",[55,56],39.22321,38.67431,{"lat":56,"lon":55},[59],{"name":41,"role":42,"phone":60,"phoneExt":30,"email":44},"05303493896",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","AHMET AKSU","Assistant Professor","100638571","hfno-flow-rates-and-cerebral-oxygenation-during-deep-sedation-for-cystoscopy-100638571",false,"NCT07630038","HFNO Flow Rates and Cerebral Oxygenation During Deep Sedation for Cystoscopy","Effect of Different Flow Rates of High-Flow Nasal Oxygen on Peripheral and Cerebral Oxygenation and Ventilation During Procedural Sedation for Cystoscopy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled to undergo elective cystoscopy under procedural sedation in an operating room setting\n* American Society of Anesthesiologists (ASA) physical status classification I-III\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known neurological disorders\n* History of ischemic or hemorrhagic stroke\n* Peripheral artery disease\n* Vasculitis\n* Severe heart failure\n* Uncontrolled hypertension\n* Uncontrolled diabetes mellitus\n* Advanced-stage chronic obstructive pulmonary disease\n* Severe anemia (hemoglobin \\\u003C8 g\u002FdL)\n* Skin lesions that could interfere with near-infrared spectroscopy (NIRS) measurements\n* History of head trauma\n* History of cranial surgery\n* Nasal deformity or nasal obstruction",true,"ALL","18 Years",{"count":76,"type":77},200,"ESTIMATED","INTERVENTIONAL",[80],"NA","For Patients and Families\n\nThis study aims to investigate how high-flow oxygen therapy affects oxygen levels, especially brain oxygenation, during cystoscopy procedures performed under sedation. The goal is to improve patient safety and comfort by ensuring better oxygen delivery during the procedure. Different oxygen flow rates will be compared, while patients' breathing, oxygen levels, and vital signs are continuously monitored throughout the procedure. All methods used in the study are consistent with routine anesthesia practices, and patient safety remains the highest priority.\n\nFor Healthcare Professionals\n\nThis prospective randomized controlled study evaluates the effects of different high-flow nasal oxygen (HFNO) flow rates on cerebral oxygenation, peripheral oxygenation, and ventilation parameters in patients undergoing cystoscopy under procedural sedation. The primary aim is to determine the contribution of HFNO to sedation safety and to provide clinical evidence regarding the optimal flow rate. In addition, hypoxemia incidence, airway intervention requirements, hemodynamic variables, and sedation depth are being analyzed.",[83,84,85,86],"Deep Sedation","High Flow Nasal Canula","Cerebral Oxygenation","PSI",[84,83,88,86],"rSO2","NOT_YET_RECRUITING","2026-06-01",{"date":92,"type":93},"2026-06-05","ACTUAL",{"date":90,"type":77},{"date":96,"type":77},"2026-10-01",{"name":5,"class":6},1]