[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100495974":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":62,"collaborators":25,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":25,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Regensburg","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"intermittent theta burst stimulation (iTBS)","EXPERIMENTAL","1200 pulses of iTBS per session with five sessions per day applied at five days (Monday-Friday) with 120% resting motor threshold",[13],"Device: high-dose accelerated intermittent theta burst stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"sham treatment","SHAM_COMPARATOR","1200 pulses of iTBS per session with five sessions per day applied at five days (Monday-Friday) with 120% resting motor threshold with angled coil",[19],"Device: sham high-dose accelerated intermittent theta burst stimulation",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DEVICE","high-dose accelerated intermittent theta burst stimulation",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"sham high-dose accelerated intermittent theta burst stimulation",[15],[30],{"name":31,"affiliation":32,"role":33},"Berthold Langguth","University Hospital of Regensburg, Department of Psychiatry and Psychotherapy at the Bezirksklinikum","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Martin Schecklmann, Prof.","CONTACT","+49-941-941-1256","martin.schecklmann@medbo.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Johannes Huebner","+49-941-941-0","johannes.huebner@medbo.de",[45],{"facility":46,"status":47,"city":48,"state":25,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Department of Psychiatry and Psychotherapy, University of Regensburg","RECRUITING","Regensburg","93055","Germany","DE",{"type":53,"coordinates":54},"Point",[55,56],12.10161,49.01513,{"lat":56,"lon":55},[59],{"name":31,"role":37,"phone":60,"phoneExt":25,"email":61},"+49-941-941-2099","berthold.langguth@medbo.de",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Berthold Langguth, MD, Ph.D.","Prof. Dr.","100495974","high-dose-accelerated-theta-burst-stimulation-for-the-treatment-of-alcohol-addiction-100495974",false,"NCT05738174","High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction","Theta Burst Zur Behandlung Der Alkoholabhängigkeit","TBA","Inclusion Criteria:\n\n* alchohol dependence according to ICD-10 (F10.2)\n* desire to reduce or abstain from alcohol drinking\n* male or female\n* 18-65 years\n* residency in Germany, German speaking\n* written informed consent\n\nExclusion Criteria:\n\n* contraindications for transcranial magnetic stimulation (electric devices or metal parts in the body such as pacemaker)\n* relevant neurological or internistic diseases according to study investigator\n* treatment with TMS in the past\n* participation in other trials during treatment\n* pregnancy or breatfeeding\n* positive breath test for alcohol\n* legal care and placement in a psychiatric hospital\n* co-medication with disulfiram, acamprosate, topiramate, baclofen, naltrexone, or nalmefene\n* acute psychiatric comorbidity that requires inpatient treatment or medication readjustment (\\\u003C1 month)\n* severe chronic psychiatric illness (schizophrenia, schizoaffective disorder, bipolar disorder)\n* patients who are unable to complete study questionnaires or follow-up questionnaires (in the opinion of the investigators)","ALL","18 Years","65 Years",{"count":78,"type":79},72,"ESTIMATED","INTERVENTIONAL",[82],"NA","This is a two-arm randomized placebo-controlled trial in which 72 patients with alcohol addiction are treated with high-dose accelerated intermittent theta burst stimulation (TBS).",[85],"Alcohol Dependence","2025-09-18",{"date":88,"type":89},"2025-09-19","ACTUAL",{"date":91,"type":89},"2023-03-01",{"date":93,"type":79},"2026-02-28",{"name":64,"class":6},1]