[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636501":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":27,"locations":33,"responsibleParty":51,"collaborators":18,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":18,"enrollmentInfo":63,"targetDuration":18,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":75,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High Intenisity Lasertherapy group","EXPERIMENTAL","The high-energy, multimodal laser therapy with thermal control (THEAL) will be administered using an Ixyon XP device (Mectronic, Bergamo, Italy), which allows the delivery of 4 wavelengths (650 nm, 810 nm, 980 nm, and 1064 nm) in continuous and pulsed mode, with an average power of up to 30 W, administering 10 sessions on alternate days.",[13],"Device: THEAL:Ixyon XP (Mectronic, Bergamo, Italy)",{"label":15,"type":16,"description":17,"interventionNames":18},"Exercise group","NO_INTERVENTION","Patients will perform exercises for 4 weeks following recruitment. Patients in this group will be taught home exercises to improve the dynamic stability of the thumb metacarpal trapezius joint. The patient is instructed to perform a flexion of the trapeziometacarpal. If the individual is able to complete 10 repetitions with good technique, resistance will be added manually or with rubber bands. If this exercise is painful, they are asked to return to active movement only. Patients in both groups will be instructed to use a brace during the day for 4 weeks following recruitment.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","THEAL:Ixyon XP (Mectronic, Bergamo, Italy)","laser therapy",[9],[26],"High Intensity laser therapy",[28],{"name":29,"role":30,"phone":31,"phoneExt":18,"email":32},"angela notarnicola","CONTACT","+393385678124","angela.notarnicola@uniba.it",[34],{"facility":35,"status":36,"city":37,"state":18,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Angela Notarnicola","RECRUITING","Bari","70124","Italy","IT",{"type":42,"coordinates":43},"Point",[44,45],16.86982,41.12066,{"lat":45,"lon":44},[48],{"name":35,"role":30,"phone":49,"phoneExt":18,"email":50},"0805592938","angelanotarnicola@yahoo.it",{"type":52,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100636501","high-energy-laser-in-the-conservative-treatment-of-rhizarthrosis-100636501",false,"NCT07566507","High-Energy Laser in the Conservative Treatment of Rhizarthrosis","High Intensity Laser Therapy (HL) vs Exercise in Thumb Osteoarthritis","HLEX-TO","Inclusion Criteria:\n\n* arthrosis of the trapezoid-metacarpal with stage 1 or 2 of the Eaton-Littler radiographic classification and pain (recent radiograph within 6 months previously);\n* clinical picture that has been occurring for at least 6 months;\n* pain scored with VAS scale at least 4\u002F10.\n\nExclusion Criteria:\n\n* rheumatoid arthritis or outcomes of trauma in the affected area, contra-indications to treatment with laser therapy (neoplasia, pregnancy, thrombocytopenia, epilepsy, uncompensated heart disease or arrhythmia, pacemaker, local infections),\n* corticosteroid infiltration or physical therapy in the previous 4 weeks.","ALL","18 Years",{"count":64,"type":65},42,"ESTIMATED","INTERVENTIONAL",[68],"NA","Osteoarthritis (OA) is a degenerative joint disease that can affect the hands and is particularly debilitating when it involves the trapeziometacarpal joint (rhizarthrosis). It causes pain, deformity, limited movement and strength, joint instability, resulting in significant limitations in daily activities.Many conservative treatments, such as medications, therapeutic exercises, physical therapy, and orthoses, are effective for managing hand OA. For patients who do not respond to conservative treatments, surgical intervention will be necessary.",[71,72,73,74],"Thumb Osteoarthritis","Hand Injuries","Laser","Exercise",[76,77,78,79,80],"hand","rehabilitation","conservative","lasertherapy","exercise","2026-05-13",{"date":83,"type":84},"2026-05-15","ACTUAL",{"date":86,"type":84},"2025-11-01",{"date":88,"type":65},"2028-12-01",{"name":5,"class":6},1]