[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507111":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":47,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Region Stockholm","OTHER_GOV",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Tight facemask or NIV",null,"Preoxygenation with tight fitting facemask or NIV (non-invasive ventilation) according to the paitents need before anaesthesia induction.",{"label":13,"type":10,"description":14,"interventionNames":15},"High Flow Nasal Oxygen and Tight facemask\u002F NIV","Pre and peri-oxygenation with HFNO using Optiflow Switch in addition to tight fitting facemask or NIV (non-invasive ventilation).",[16],"Device: Optiflow Switch",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DEVICE","Optiflow Switch","High flow nasal oxygen with the Optiflow Switch device",[13],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Ida-Maria Forsberg, PhD","CONTACT","+ 46704381445","ida-maria.forsberg@regionstockholm.se",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Karolinska University Hospital","RECRUITING","Stockholm","Stockholm County","17176","Sweden","SE",{"type":39,"coordinates":40},"Point",[41,42],18.06871,59.32938,{"lat":42,"lon":41},[45],{"name":25,"role":26,"phone":46,"phoneExt":10,"email":28},"+46704381445",{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[50],{"name":51,"class":52},"Karolinska Institutet","OTHER","100507111","high-flow-nasal-oxygenation-for-apnoeic-oxygenation-during-intubation-of-the-critically-ill-100507111",false,"NCT05883137","High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill","High-flow Nasal Oxygenation for Apnoeic Oxygenation With Optiflow Switch During Intubation of the Critically Ill Adult- a Prospective Before-and-after Study","HiPOXIC","Inclusion Criteria:\n\n* Adult, ≥18 years old\n* Intensive care patients that require tracheal intubation for any indication\n\nExclusion Criteria:\n\n* Patients with skull or facial injuries where the application of nasal cannula is to be avoided, decided by the intensivist.\n* Pregnancy\n* Total nasal obstruction\n* Deemed not suitable for any other reason than the aforementioned","ALL","18 Years","100 Years",{"count":65,"type":66},150,"ESTIMATED","OBSERVATIONAL","Intubation in the intensive care unit is a standard procedure with a high risk of adverse events such as hypoxaemia and cardiovascular instability. However, it is demonstrated that HFNO (High Flow Nasal Oxygen) for pre and perioxygenation is feasible and, in many situations, prolongs the safe apnoeic period after anaesthesia induction. Previous data of the use of HFNO during intubation of the critically ill is conflicting.\n\nWith the new device Optiflow Switch, which allow its combination with NIV or tight facemask with perioxygenation, we aim to evaluate whether this could reduce intubation-related hypoxaemia and other adverse events.\n\nThe general purpose of this project is to compare the addition of Optiflow Switch for pre- and perioxygenation to traditional preoxygenation using a tight-fitting mask or NIV during intubation in adult intensive care patients in a prospective before-and-after study design.",[70,71,72,73],"Critical Illness","Respiratory Failure","Multi Organ Failure","Hypoxia",[75,76,77,78],"Apnoeic oxygenation","Airway management","Intensive care","Critical care","2025-04-10",{"date":81,"type":82},"2025-04-11","ACTUAL",{"date":84,"type":82},"2023-09-25",{"date":86,"type":66},"2026-06-30",{"name":5,"class":6},1]