[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603601":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":22,"locations":27,"responsibleParty":42,"collaborators":7,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":7,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":57,"studyType":58,"phases":7,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":7,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"The Affiliated Hospital of Xuzhou Medical University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DEVICE","High-Frequency QRS","All enrolled patients underwent HF-QRS assessment, with subsequent recording of MACE to evaluate the predictive value of HF-QRS parameters for clinical outcomes",[14,18],{"name":15,"affiliation":16,"role":17},"Yong Huo, Ph.D","Department of Cardiology, Peking University First Hospital, Beijing, China","STUDY_CHAIR",{"name":19,"affiliation":20,"role":21},"Yuan Lu, Ph.D","The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002","STUDY_DIRECTOR",[23],{"name":19,"role":24,"phone":25,"phoneExt":7,"email":26},"CONTACT","13952110901","405983931@qq.com",[28],{"facility":5,"status":7,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Xuzhou","Jiangsu","221000","China","CN",{"type":35,"coordinates":36},"Point",[37,38],117.28386,34.20442,{"lat":38,"lon":37},[41],{"name":19,"role":24,"phone":25,"phoneExt":7,"email":26},{"type":43,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100603601","high-frequency-qrs-for-predicting-microvascular-dysfunction-and-adverse-events-after-pci-in-acute-myocardial-infarction-100603601",false,"NCT07138638","High-Frequency QRS for Predicting Microvascular Dysfunction and Adverse Events After PCI in Acute Myocardial Infarction","High-Frequency QRS for Predicting Microvascular Dysfunction and Adverse Events After PCI in Acute Myocardial Infarction: A Prospective, Multicenter Cohort Study","Inclusion Criteria:\n\n* Aged 18 to 75 years (inclusive)\n\nDiagnosed with acute myocardial infarction (AMI, including STEMI and NSTEMI) and underwent successful emergency PCI\n\nVoluntarily participated and provided written informed consent\n\nExclusion Criteria:\n\n* History of prior myocardial infarction or chronic heart failure\n\nQRS duration \\>120 ms (including paced rhythm, WPW syndrome, bundle branch block, or left ventricular hypertrophy with repolarization abnormalities)\n\nStructural heart disease (congenital heart disease, cardiomyopathy, aortic dissection, etc.)\n\nPersistent atrial fibrillation or malignant arrhythmias\n\nHistory of cerebral hemorrhage or ischemic stroke within 1 month\n\nProlonged cardiopulmonary resuscitation or requiring advanced life support (IABP\u002FECMO, etc.)\n\nScheduled for imminent surgery with anticipated inability to complete HF-QRS assessment\n\nOther life-threatening conditions including: Severe hepatic or renal dysfunction;Uncontrolled systemic diseases;Hematologic disorders;Active infections;Malignancy with life expectancy \\\u003C1 year Other investigator-determined exclusionary conditions:Pregnancy;Concurrent participation in other clinical trials\n\nRefusal to participate in the clinical study","ALL","18 Years","75 Years",{"count":55,"type":56},1112,"ESTIMATED","1 Year","OBSERVATIONAL","This observational study aimed to investigate the prognostic value of high-frequency QRS (HF-QRS) in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI), as well as its potential role in diagnosing microvascular dysfunction. The main question it aims to answer is:\n\n1. Whether HF-QRS could serve as an effective tool for early identification of high-risk AMI patients and prognosis prediction;\n2. Whether HF-QRS provides auxiliary diagnostic value for post-AMI microvascular dysfunction.\n\nParticipants underwent HF-QRS assessment and were prospectively followed for 1 year to record the incidence of major adverse cardiovascular events (MACE).",[61],"AMI",[63,11,64,65],"Acute Myocardial Infarction","prediction model","Microvascular Dysfunction","NOT_YET_RECRUITING","2025-08-16",{"date":69,"type":70},"2025-08-24","ACTUAL",{"date":72,"type":56},"2025-08",{"date":74,"type":56},"2027-12",{"name":5,"class":6},1]