[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100465768":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":50,"locations":59,"responsibleParty":88,"collaborators":24,"id":90,"slug":91,"hasResults":92,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":24,"eligibilityCriteria":96,"healthyVolunteers":92,"sex":97,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":24,"studyType":103,"phases":104,"briefSummary":106,"conditions":107,"keywords":115,"overallStatus":62,"whyStopped":24,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":128},{"fullName":5,"class":6},"Aristotle University Of Thessaloniki","OTHER",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"TECAR therapy","EXPERIMENTAL","Participants in this arm receive high-frequency electrical current transfer (TECAR) using the Winback system at 0.5 MHz in capacitive mode with 40-60% intensity. In the acute phase, participants receive a single 20-minute session for acute hamstring strain or acute low back pain. In the chronic phase, participants receive 10 sessions (3 times per week) for hamstring injury or chronic low back pain.",[13,14],"Device: Radiofrequency Energy Transfer","Device: Transcutaneous Nerve Stimulation",{"label":16,"type":17,"description":18,"interventionNames":19},"TENS Therapy","ACTIVE_COMPARATOR","Participants in this arm receive transcutaneous electrical nerve stimulation (TENS) using a Chattanooga system with an asymmetric biphasic mode at 80 Hz. In the acute phase, participants receive a single 20-minute session for acute hamstring strain or acute low back pain. In the chronic phase, participants receive 10 sessions (3 times per week) for hamstring injury or chronic low back pain.",[13,14],{"label":21,"type":22,"description":23,"interventionNames":24},"Control group","NO_INTERVENTION","Participants in this arm serve as the control group and do not receive any active electrophysical intervention during the assessment periods. For the acute phase, outcomes are measured over a 48-hour window. For the chronic phase, outcomes are measured at baseline and follow-up intervals to account for natural recovery and baseline variations.",null,[26,33],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DEVICE","Radiofrequency Energy Transfer","Radiofrequency Electrical Currents (TECAR) will be delivered using a winback system (Winback, Villeneuve-Loubet, France) propagating radiofrequency waves of 448 kHz using metallic electrodes via a coupling medium. Radiofrequencies will be used in the capacitive mode , which aims to treat superficial \u002Fsoft tissues in the area. The \"active\" plate will be applied sequentially on the skin in the injured or painful region. The base plate will be located to the other side of the injured body region (for back thigh muscle injuries, for example, the base plate will be located on the frontal thigh area, to close the current circuit. Therapy will be applied for 20 minutes, with a target intensity of 40% and a frequency of 0.5Mhz.",[9,16],[32],"TECAR",{"type":27,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"Transcutaneous Nerve Stimulation","Transcutaneous nerve stimulation (TENS) will be delivered using a Chattanooga Intellect Advanced Combo system (Chattanooga, Hixson, TN 3 7343, USA). Two electrodes will be placed on the skin at a distance so that they cover the entire painful area. The TENS asymmetric biphasic mode (phase 300 ms, frequency 80Hz, continuous cycle) will be applied. The intensity will be adjusted between 0 and 110A, such that it is tolerable by the participant. The total application time will be 20 minutes or equal to that applied for the TECAR group.",[9,16],[38],"TENS",[40,44,48],{"name":41,"affiliation":42,"role":43},"Eleftherios Kellis, Ph.D.","Professor","PRINCIPAL_INVESTIGATOR",{"name":45,"affiliation":46,"role":47},"Thomas Apostolou, M.D.","International Hellenic University","STUDY_DIRECTOR",{"name":49,"affiliation":46,"role":43},"Paris Iakovidis, Ph.D.",[51,55],{"name":41,"role":52,"phone":53,"phoneExt":24,"email":54},"CONTACT","+302310991053","ekellis@phed-sr.auth.gr",{"name":56,"role":52,"phone":57,"phoneExt":24,"email":58},"Anna Kellis, MSc","+302510240610","anna24kellis@google.com",[60,77],{"facility":61,"status":62,"city":63,"state":24,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"Physiotherapy Clinic","RECRUITING","Kavala","64100","Greece","GR",{"type":68,"coordinates":69},"Point",[70,71],24.40687,40.93959,{"lat":71,"lon":70},[74],{"name":75,"role":52,"phone":24,"phoneExt":24,"email":76},"Anna Kelli, MSc","physiokelli@gmail.com",{"facility":78,"status":62,"city":79,"state":24,"zip":80,"country":65,"countryCode":66,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Laboratory of Neuromechanics, Department of Physical Education and Sport Science, Aristotle University of Thessaloniki","Serres","62100",{"type":68,"coordinates":82},[83,84],23.54757,41.08499,{"lat":84,"lon":83},[87],{"name":41,"role":52,"phone":24,"phoneExt":24,"email":54},{"type":43,"investigatorFullName":89,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Eleftherios Kellis","100465768","high-frequency-rf-current-effects-on-muscle-pain-and-function-100465768",false,"NCT05345015","High Frequency RF Current Effects on Muscle Pain and Function","Acute and Chronic Effects of High Frequency RF Electrical Current on Pain and Muscle Function in Individuals With Musculoskeletal Pain","Individuals with Muscle Injury\n\nInclusion Criteria:\n\n* Age over 18 years.\n* Athletes: amateur soccer players or sprinters with regular, systematic training.\n* Suspected Grade I or II hamstring strain.\n* Cessation of training due to injury.\n* No surgical intervention in the previous year (for initial assessment as potential participants).\n\nExclusion Criteria:\n\n* History of injury to the same muscle (ipsilateral side) within the last 6 months.\n* Other injury to the posterior aspect of the thigh.\n* Other injuries or chronic pain in the trunk or lower limbs.\n* Use of non-steroidal anti-inflammatory drugs (NSAIDs) in the 3 months prior to the injury.\n\nIndividuals with Acute Low Back Pain\n\nInclusion Criteria:\n\n* Age over 18 years.\n* Pain located between the lower ribs and the gluteal folds (top of the buttocks).\n* Pain occurred on fewer than half of the days over the preceding six months.\n* Pain intensity $\\\\ge$ 6\u002F10 on the Visual Analogue Scale (VAS).\n* Pain related to one or more of the following:\n\n  * Lumbar facet joints\n  * Sacroiliac joints\n  * Lumbar intervertebral discs\n  * Muscles, tendons, or ligaments of the lumbar and sacral region\n  * Other bony structures of the lumbar spine\n* Discontinuation of non-steroidal anti-inflammatory drugs (NSAIDs) or analgesics:\n\n  * 1 day prior to measurement\n  * 48 hours after measurement\n\nExclusion Criteria:\n\n* Radiographic evidence of inflammatory disease affecting the spine.\n* Spinal fracture.\n* Significant genetic structural abnormality of the spine.\n* Pregnancy.\n* Psychiatric disorders.\n* Receipt of systemic medication or treatment in the last 3 months.\n* Presence of neurological deficits (sensory, motor, or reflexes).\n* Receipt of TENS or TECAR therapy within the last year.\n\nIndividuals with Chronic Low Back Pain\n\nInclusion Criteria:\n\n* Episodes of low back pain (between the lower rib margin and the gluteal fold) for at least half of the days during the last 6 months.\n* Pain intensity $\\\\ge$ 20% on the Visual Analogue Scale (VAS).\n\nExclusion Criteria:\n\n* Spinal stenosis.\n* Radiographic evidence of inflammatory disease affecting the spine.\n* Vertebral fracture.\n* Presence of spondylolisthesis or spondylolytic lesion (spondylolysis).\n* Significant genetic structural abnormality of the spine.\n* Daily, severe low back pain.\n* Pregnancy.\n* Use of medications that might influence heart rate or blood pressure.\n* Psychiatric disorders.","ALL","18 Years","65 Years",{"count":101,"type":102},200,"ESTIMATED","INTERVENTIONAL",[105],"NA","The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called \"TECAR\") on pain and functional movement in individuals with a musculoskeletal injury or pain. The participants will be assigned into an experimental or a control group and outcome measures will be measured prior to, after, 24 and 48 hours following a single intervention session (Acute effects) as well as 3 and 6 months after the intervention (chronic effects).",[108,109,110,111,112,113,114],"Transcutaneous Electric Nerve Stimulation","Chronic Low-back Pain","Hamstring Injury","Muscle; Injury, Quadriceps (Thigh)","Physical Therapy","Calf Muscle Pulled","Acute Low Back Pain",[116,9,117,118],"Sport injuries","Low back pain","Muscle injury","2026-06-23",{"date":121,"type":122},"2026-06-26","ACTUAL",{"date":124,"type":122},"2022-09-01",{"date":126,"type":102},"2029-12-31",{"name":5,"class":6},2]