[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644720":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":29,"centralContacts":30,"locations":29,"responsibleParty":36,"collaborators":29,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":29,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":29,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":63,"whyStopped":29,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":29},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"High-frequency short-course extracorporeal shock wave therapy (ESWT)","EXPERIMENTAL","Participants receive daily ESWT for 7 consecutive days (7 total sessions within 1 week). Standard treatment parameters for each session: 2000 shocks, 10 Hz frequency, energy flux density of 0.1-0.25 mJ\u002Fmm² (adjusted gradually per patient tolerance). The treatment site is the most tender area over the rotator cuff, confirmed by palpation and ultrasound guidance. All participants also receive standardized activity modification guidance and home rehabilitation exercises. Oral non-steroidal anti-inflammatory drugs (NSAIDs) are permitted and recorded; other physical therapies are prohibited during active treatment.",[13],"Device: Arm 1 Intervention Name: High-frequency short-course extracorporeal shock wave therapy Arm 2 Intervention Name: High-frequency intensive extracorporeal shock wave therapy Arm 3 Intervention Name: Conv",{"label":15,"type":10,"description":16,"interventionNames":17},"High-frequency intensive ESWT","Participants complete 3 cycles of ESWT. Each cycle consists of 7 consecutive daily ESWT sessions, with a 1-week rest interval between cycles (21 total sessions over 7 weeks). Identical ESWT parameters are used for every session: 2000 shocks, 10 Hz frequency, energy flux density of 0.1-0.25 mJ\u002Fmm² (adjusted per patient tolerance), targeting the tender rotator cuff area confirmed by ultrasound. All participants receive unified activity advice and home rehabilitation exercises. Oral NSAIDs are allowed and documented; additional physical therapies are not permitted during treatment.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Conventional ESWT (Active Comparator)","ACTIVE_COMPARATOR","Participants receive ESWT once per week for 7 consecutive weeks (7 total sessions over 7 weeks). Each session uses the same standardized parameters as the other two arms: 2000 shocks, 10 Hz frequency, energy flux density of 0.1-0.25 mJ\u002Fmm², with the treatment location guided by palpation and ultrasound. All participants follow the same activity modification instructions and home exercise program. Oral NSAIDs are permitted (recorded), and other physical interventions are restricted during the active treatment period.",[13],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","Arm 1 Intervention Name: High-frequency short-course extracorporeal shock wave therapy Arm 2 Intervention Name: High-frequency intensive extracorporeal shock wave therapy Arm 3 Intervention Name: Conv","Arm 1: 7 daily sessions, 1 total week (single short cycle) Arm 2: 3 cycles of 7 daily sessions + 1-week rest between cycles, 7 total weeks (intensive multi-cycle) Arm 3: 7 weekly sessions, 7 total weeks (traditional low-frequency)",[19,15,9],null,[31],{"name":32,"role":33,"phone":34,"phoneExt":29,"email":35},"Xiali Xue, Dr","CONTACT","+86 18483638915","390231882@qq.com",{"type":37,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100644720","high-frequency-short-course-extracorporeal-shock-wave-therapy-for-partial-rotator-cuff-tears-study-protocol-for-a-multicenter-randomized-controlled-trial-100644720",false,"NCT07673055","High-frequency Short-course Extracorporeal Shock Wave Therapy for Partial Rotator Cuff Tears: Study Protocol for a Multicenter, Randomized, Controlled Trial","Inclusion Criteria:\n\n* Age 30-70 years, male or female\n* MRI- or high-resolution ultrasound-confirmed partial-thickness rotator cuff tear (predominantly supraspinatus) or small full-thickness tear without retraction or displacement\n* Shoulder pain duration ≥3 months with Visual Analog Scale (VAS) score ≥4 (0-10 scale)\n* Willing and able to provide written informed consent and comply with the study protocol\n\nExclusion Criteria:\n\n* Large or massive full-thickness rotator cuff tear, tear with Grade II retraction or greater, or presence of a greater tuberosity bone cyst\n* Severe muscle fatty infiltration (Goutallier grade ≥3) on MRI\n* Uncontrolled diabetes mellitus (HbA1c \\>7.5%), hypothyroidism, or heavy smoking (≥20 pack-years)\n* Received local injection therapy (e.g., corticosteroids, platelet-rich plasma) to the affected shoulder within 4 weeks prior to enrollment\n* Concurrent shoulder pathologies including glenohumeral osteoarthritis, adhesive capsulitis (frozen shoulder), or shoulder instability\n* Systemic diseases (e.g., rheumatoid arthritis), bleeding disorders, or coagulopathy\n* Pregnancy or lactation\n* Contraindications to ESWT (e.g., cardiac pacemaker, malignancy at treatment site)\n* Inability to complete treatment or follow-up schedule",true,"ALL","30 Years","70 Years",{"count":49,"type":50},300,"ESTIMATED","INTERVENTIONAL",[53],"NA","This is a multicenter, randomized controlled clinical study exploring three different extracorporeal shock wave therapy (ESWT) regimens for patients with partial rotator cuff tears, a common cause of chronic shoulder pain and limited movement. Traditional ESWT uses a once-weekly treatment schedule over 7 weeks, which takes a long time and leads to low patient compliance. This study aims to test two new high-frequency, short-course ESWT protocols, compare their pain relief, shoulder function improvement, tendon healing effect, safety and treatment adherence with the conventional regimen, and finally establish a more efficient, patient-friendly standardized treatment plan for clinical use. A total of 300 eligible participants will be recruited from 10 top-tier hospitals across China and followed up for 12 months after treatment.",[56],"Partial Rotator Cuff Tears (PRCTs)",[58,59,60,61,62],"Partial rotator cuff tears","Extracorporeal shock wave therapy","High-frequency short-course therapy","Shoulder pain","Treatment adherence","NOT_YET_RECRUITING","2026-06-22",{"date":66,"type":67},"2026-06-29","ACTUAL",{"date":69,"type":50},"2027-01-01",{"date":71,"type":50},"2030-01-01",{"name":5,"class":6}]