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Instituut","Tilburg",{"type":44,"coordinates":225},[226,227],5.0913,51.55551,{"lat":227,"lon":226},{"facility":230,"status":98,"city":231,"state":10,"zip":10,"country":41,"countryCode":42,"cosmosGeoPoint":232,"geoPoint":236,"contacts":10},"Maxima Medisch Centrum","Veldhoven",{"type":44,"coordinates":233},[234,235],5.40278,51.41833,{"lat":235,"lon":234},{"facility":238,"status":39,"city":239,"state":10,"zip":10,"country":41,"countryCode":42,"cosmosGeoPoint":240,"geoPoint":244,"contacts":10},"Zaans Medisch Centrum","Zaandam",{"type":44,"coordinates":241},[242,243],4.82643,52.43854,{"lat":243,"lon":242},{"type":18,"investigatorFullName":246,"investigatorTitle":247,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Berdine Heesterman","Principal Investigator","100510821","high-risk-prostate-cancer-radiation-versus-surgery-100510821",false,"NCT05931419","High-Risk prostatE Cancer radiatiOn Versus surgERy","High-Risk prostatE Cancer radiatiOn Versus surgERy (RECOVER)","RECOVER","Inclusion Criteria:\n\n* Histologically confirmed de novo non-metastatic high-risk prostate cancer.\n* cT3a-bN0M0, according to the 8th edition of the Tumour, Node, Metastasis (TNM) classification, with the exception that clinical T-stage will be based on digital rectal examination and magnetic resonance imaging (the highest stage will be used) and\u002For\n* International Society of Urological Pathology (ISUP) grade ≥4 and\u002For\n* Prostate-Specific Antigen (PSA) value at diagnosis greater than 20 ng\u002FmL\n* Fit for treatment with either RARP or EBRT +\u002F- ADT (WHO performance status 0-1)\n* Living in the Netherlands\n* Able to read and understand the Dutch language\n\nExclusion Criteria:\n\n* Histological types other than adenocarcinoma\n* Diagnosis and\u002For treatment in a hospital abroad\n* Treatment with Androgen Receptor Targeted Agents (ARTA) as part of the initial treatment plan","MALE","50 Years","75 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