[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628078":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":40,"locations":46,"responsibleParty":61,"collaborators":44,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":44,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":44,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":48,"whyStopped":44,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Fenerbahce University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High-Intensity Interval Training (HIIT)","EXPERIMENTAL","Participants assigned to the HIIT group will perform High-Intensity Interval Training on a cycle ergometer. The protocol consists of a 5-minute warm-up at 50% of maximum heart rate (HRmax), followed by five cycles of 1 minute at 80% HRmax and 2 minutes of active recovery at 60% HRmax, and a 5-minute cool-down at 50% HRmax. Sessions will be conducted three times per week for 6 weeks. Exercise intensity will be progressively increased by 5% every two weeks. All sessions will be supervised by a physiotherapist.",[13],"Behavioral: High-Intensity Interval Training (HIIT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Moderate-Intensity Continuous Training (MCIT)","ACTIVE_COMPARATOR","Participants assigned to the MCIT group will perform Moderate-Intensity Continuous Training on a cycle ergometer. The protocol consists of a 5-minute warm-up at 50% of maximum heart rate (HRmax), followed by 20 minutes of continuous exercise at 80% HRmax, and a 5-minute cool-down at 50% HRmax. Sessions will be conducted three times per week for 6 weeks. Exercise intensity will be progressively increased by 5% every two weeks. All sessions will be supervised by a physiotherapist.",[19],"Behavioral: Moderate-Intensity Continuous Training (MCIT)",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","High-Intensity Interval Training (HIIT) will be delivered on a cycle ergometer under physiotherapist supervision. Each session includes a 5-minute warm-up at 50% of maximum heart rate (HRmax), followed by five cycles of 1 minute at 80% HRmax and 2 minutes of active recovery at 60% HRmax, and a 5-minute cool-down at 50% HRmax. Sessions will be performed 3 times per week for 6 weeks, with intensity progressed by 5% every two weeks as tolerated.",[9],[26],"HIIT",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Moderate-Intensity Continuous Training (MCIT) will be delivered on a cycle ergometer under physiotherapist supervision. Each session includes a 5-minute warm-up at 50% of maximum heart rate (HRmax), followed by 20 minutes of continuous exercise at 80% HRmax, and a 5-minute cool-down at 50% HRmax. Sessions will be performed 3 times per week for 6 weeks, with intensity progressed by 5% every two weeks as tolerated.",[15],[31],"MCIT",[33,37],{"name":34,"affiliation":35,"role":36},"Sümeyye Akçay, Asst. Prof.","Fenerbahçe University","PRINCIPAL_INVESTIGATOR",{"name":38,"affiliation":39,"role":36},"Arzu Dinç Yavaş, MD","Istanbul Aydın University",[41],{"name":34,"role":42,"phone":43,"phoneExt":44,"email":45},"CONTACT","+905424002553",null,"smyye.akcy@gmail.com",[47],{"facility":35,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":44,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Istanbul","Ataşehir","34758","Turkey (Türkiye)",{"type":54,"coordinates":55},"Point",[56,57],28.94966,41.01384,{"lat":57,"lon":56},[60],{"name":34,"role":42,"phone":43,"phoneExt":44,"email":45},{"type":36,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":44,"oldOrganization":44},"Sümeyye Akçay","Asst. Prof.","100628078","hiit-vs-mcit-for-stroke-related-sarcopenia-in-ischemic-stroke-100628078",false,"NCT07456956","HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke","The Effect of High-Intensity Interval Training Versus Moderate-Intensity Continuous Training on Sarcopenia and Clinical Outcomes in Patients With Ischemic Stroke: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* First-ever stroke.\n* Age 18 years or older.\n* Diagnosis of ischemic stroke.\n* Stroke duration between 1-6 months (subacute phase).\n* Modified Rankin Scale score \\\u003C 3.\n* Mini-Mental State Examination (MMSE) score ≥ 24.\n* Brunnstrom lower extremity motor stage between Stage III-V.\n* Lower extremity functional capacity sufficient to allow exercise participation (able to ambulate at least with an assistive device).\n* Lower extremity spasticity ≤ 2 according to the Modified Ashworth Scale.\n* Independent sitting balance (able to sit unsupported for at least 30 seconds).\n* Presence of sufficient voluntary active movement in the lower extremity to permit exercise application.\n* Ability to communicate.\n* Willingness to participate in the study and provision of written informed consent.\n\nExclusion Criteria:\n\n* Presence of hemispatial neglect.\n* History of recurrent stroke.\n* Presence of a psychiatric disorder.\n* Presence of orthopedic, neurological, or cardiopulmonary conditions that would contraindicate the planned exercise protocols.","ALL","18 Years","80 Years",{"count":75,"type":76},32,"ESTIMATED","INTERVENTIONAL",[79],"NA","The aim of this study is to investigate the effect of post-stroke sarcopenia on prognosis and clinical outcomes in patients with ischemic stroke and to compare the effects of High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MCIT) exercise programs on muscle mass, as well as on functional capacity, quality of life, and clinical outcomes.",[82,83],"Stroke, Ischemic","Sarcopenia",[85,86,26,31,87,88],"Ischemic Stroke","Stroke-Related Sarcopenia","Exercise Training","Muscle Thickness","2026-03-22",{"date":91,"type":92},"2026-03-25","ACTUAL",{"date":94,"type":92},"2026-03-02",{"date":96,"type":76},"2027-06-06",{"name":5,"class":6},1]