[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100465494":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":45,"locations":54,"responsibleParty":75,"collaborators":30,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":30,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":57,"whyStopped":30,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Charles University, Czech Republic","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Individual physiotherapy (SMA-SOC)","ACTIVE_COMPARATOR","Individual physiotherapy will be performed according to the recommended SMA-SOC guidelines.",[13],"Procedure: Individual physiotherapy (SMA-SOC)",{"label":15,"type":16,"description":17,"interventionNames":18},"Hippotherapy by the children with cerebral palsy","EXPERIMENTAL","Hippotherapy by the children with cerebral palsy is an accredited form of hippotherapy, whose methodology is based on the clinical picture of cerebral palsy, but its procedures are applicable to a wider group of children with disabilities. Therefore, investigators assume its effect for children with SMA.",[19],"Procedure: Hippotherapy",{"label":21,"type":6,"description":22,"interventionNames":23},"Therapeutic grooming","In order to influence the psychomotor development in a comprehensive way, the psychosocial activity of therapeutic grooming will also be included in the study. Its goal is to support children's communication, their interaction with the environment, the ability to establish contact with the horse and the overall emotional support of children with SMA.",[24],"Procedure: Therapeutic grooming",[26,31,37],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Therapeutic procedures according to the recommended standard (SMA-SOC) will be used in the therapy. Elements of breathing gymnastics, vibration techniques, stretching, eccentric and concentric exercise procedures will be combined. Individual physiotherapy will be conducted on the basis of set goals from the kinesiological examination, it will be adapted to the individuality of the child - his cooperation, fatigue and sleep time.",[9],null,{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"Hippotherapy","HT by CP is an accredited form of hippotherapy, whose methodology is based on the clinical picture of cerebral palsy, but its procedures are applicable to a wider group of children with disabilities. Therefore, investigators anticipate it´s effect for children with SMA.\n\nBased on a special type of examination, this method precisely determines the \"type \u002F breed\" of the horse according to the biomechanics of the movement of its back in the step, the position of the child and the neurophysiological function of the back - differentiation or sensorimotor skills. Furthermore, according to the course of therapy, the physiotherapist determines the pace of the horse's step, its length, selects special manual contacts according to the current situation and adjusts the duration of therapy to the client's fatigue.\n\nTherapy will be performed by therapists with professional competence to perform hippotherapy by children with CP.",[15],[36],"Hippotherapy by the children with cerebral palsy (HT by CP)",{"type":27,"name":21,"description":38,"armGroupLabels":39,"otherNames":30},"In order to influence the psychomotor development in a comprehensive way, the psychosocial activity of therapeutic grooming will also be included in the study. Its goal is to support children's communication, their interaction with the environment, the ability to establish contact with the horse and the overall emotional support of children with SMA. The purpose of this activity is to clean the horse, its possible guide, stroking and contact with the horse, work from the ground.",[21],[41],{"name":42,"affiliation":43,"role":44},"Kamila Rasova, as.prof.Dr.","Clinic of rheumatology and rehabilitation, Third medical faculty CU and Faculty Thomayer Hospital","STUDY_DIRECTOR",[46,50],{"name":42,"role":47,"phone":48,"phoneExt":30,"email":49},"CONTACT","+420604511416","kamila.rasova@lf3.cuni.cz",{"name":51,"role":47,"phone":52,"phoneExt":30,"email":53},"Kateřina Marikova, Mgr.","+420607616104","katerina.marikova@chmirakl.cz",[55],{"facility":56,"status":57,"city":58,"state":30,"zip":59,"country":60,"countryCode":30,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Kamila Řasová","RECRUITING","Prague","128 00","Czechia",{"type":62,"coordinates":63},"Point",[64,65],14.42076,50.08804,{"lat":65,"lon":64},[68,71],{"name":69,"role":47,"phone":48,"phoneExt":30,"email":70},"Kamila Řasová, Ph.D.","kamila.rasova@gmail.com",{"name":72,"role":47,"phone":73,"phoneExt":30,"email":74},"Natalia Hrušková","+420702836959","natalia0087@gmail.com",{"type":76,"investigatorFullName":56,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","assoc. prof. PhDr. Kamila Řasová, Ph.D.","100465494","hippotherapy-in-children-with-spinal-muscular-atrophy-100465494",false,"NCT05341453","Hippotherapy in Children With Spinal Muscular Atrophy","The Effect of Intensive Hippotherapy on the Psychomotoric Development of Children With Spinal Muscular Atrophy","HIPOSMA","Inclusion Criteria:\n\n* clinic diagnosis SMA (I, II, and III types)\n* no changing medicine 6 months at least\n* without another grave diseases\n\nExclusion Criteria:\n\n* hip subluxation\n* allergies to horses and the environment of horse stables\n* insurmountable fear of the horse","ALL","1 Year","10 Years",{"count":90,"type":91},16,"ESTIMATED","INTERVENTIONAL",[94],"NA","The randomized controlled trial is aimed to discover the physiotherapy and hippotherapy effect and efficacy on children with SMA. The concept is to utilized two types of physiotherapy - the first concept is classic physiotherapy and the second one is hippotherapy. The hippotherapy concept will be in intervals of 15 minutes twice a day, the physiotherapy will be in intervals of 30 minutes once a day. In-patient therapy will be for 6 days. The efficacy will be assessed by biomedical measures - Qualisys Motion Capture Systems 2020.3., by molecular biological markers (lncRNA) in blood and by surface electromyography (EMG). The primary goal of this study is to compare two physiotherapeutic approaches - the recommended form of classical physiotherapy and the method on a neurophysiological basis - hippotherapy. The secondary intention of the research will be the appropriate intensity of therapy so that unwanted muscle fatigue does not occur.",[97],"Spinal Muscular Atrophy",[99,100,101,102,103,104,105,106,107],"hippotherapy","children","psychomotor development","physiotherapy","quality of life","posture","motor skills","therapeutic riding","muscle fatigue","2024-08-19",{"date":110,"type":111},"2024-08-20","ACTUAL",{"date":113,"type":111},"2022-04-22",{"date":115,"type":91},"2025-10-22",{"name":5,"class":6},1]