[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053550":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":49,"collaborators":18,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":18,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":18,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Holmium Laser Enucleation of Prostate (HoLEP)","EXPERIMENTAL","Patients in this arm will undergo holmium laser enucleation of the prostate (HoLEP) for the treatment of lower urinary tract symptoms (LUTS). Patients will undergo HoLEP one time and will return for standard of care follow up.",[13],"Procedure: Holmium Laser Enucleation of Prostate (HoLEP)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Arm","NO_INTERVENTION","Patients in this arm will undergo no additional interventions and will not undergo holmium laser enucleation of the prostate (HoLEP) for the treatment of lower urinary tract symptoms and instead follow standard of care treatment and follow up.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"PROCEDURE","Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment use for men with bothersome lower urinary tract symptoms (LUTS) to improve their LUTS. During the procedure a thin telescope-like instrument is inserted into the urethra. The high-powered laser is then inserted through this instrument and used to carefully remove the excess prostate tissue that is causing obstruction of the urethra and contributing to the patient's lower urinary tract symptoms.",[9],[25],{"name":26,"affiliation":5,"role":27},"Bristol Whiles, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Jane Ledesma, BS","CONTACT","(913) 588-8721","jledesma2@kumc.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":18},"University of Kansas Health System","RECRUITING","Kansas City","Kansas","66160","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-94.62746,39.11417,{"lat":47,"lon":46},{"type":27,"investigatorFullName":26,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Principal Investigator","100053550","holep-prior-to-radiation-therapy-for-patients-with-lutsretention-and-concurrent-prostate-cancer-100053550",false,"NCT03802851","HoLEP Prior to Radiation Therapy for Patients With LUTS\u002FRetention and Concurrent Prostate Cancer","HOLEP-RTPC","Inclusion Criteria:\n\n* Patients must be 18 years of age or older\n* Patients must have bothersome lower urinary tract symptoms (LUTS), defined by American Urological Association Symptom Score (AUA SS) of greater than or equal to 15 and\u002For as defined by a post-void residual of greater than or equal to 350mL and\u002For as defined by catheter dependence\n* Patients must be diagnosed with prostate cancer by pathological tissue analysis\n* Patients must have elected for radiation with androgen deprivation therapy as the primary treatment modality for their prostate cancer\n\nExclusion Criteria:\n\n* Patients who are under 18 years of age are not eligible\n* Patients who have a diagnosis of bladder cancer are not eligible.\n* Patients with prior treatment for prostate cancer are not eligible.\n* Patients with any type of prior prostate surgery (minimally invasive, endoscopic, or otherwise) including prior transurethral resection of the prostate (but excluding prior prostate biopsy) are ineligible.\n* Patients with known metastatic prostate cancer are ineligible\n* Patients who are enrolled in other surgical or international trials at the time of this study are not eligible","ALL","18 Years",{"count":61,"type":62},30,"ESTIMATED","INTERVENTIONAL",[65],"NA","To determine if holmium laser enucleation of the prostate (HoLEP) for the treatment of lower urinary tract symptoms (LUTS) and\u002For urinary retention alters the treatment course for patients concurrently diagnosed with prostate cancer.",[68,69],"Prostate Cancer","Lower Urinary Tract Symptoms","2026-07-09",{"date":72,"type":73},"2026-07-13","ACTUAL",{"date":75,"type":73},"2019-09-19",{"date":77,"type":62},"2035-01",{"name":5,"class":6},1]