[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583907":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":20,"centralContacts":35,"locations":20,"responsibleParty":41,"collaborators":45,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":20,"enrollmentInfo":61,"targetDuration":20,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":79,"overallStatus":92,"whyStopped":20,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":20},{"fullName":5,"class":6},"National Taiwan University Hospital","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","The HI-HOPE Project implements a three-phase intervention over 48 weeks, integrating cognitive, physical, and social engagement strategies.\n\nPhase 1 (12 Weeks): Focuses on cognitive stimulation, depression relief, and music-based movement therapy. Includes weekly high-intensity exercise (3 hours\u002Fweek).\n\nPhase 2 (12 Weeks): Covers all six ICOPE domains with community-led wellness sessions and weekly high-intensity exercise (3 hours\u002Fweek).\n\nPhase 3 (12 Weeks): Intensive strength and mobility training (2 hours\u002Fweek).\n\nReferral Process: Individuals with abnormal screenings receive personalized support, including transportation aid, financial assistance, telehealth, and group referrals.\n\nDigital Health: Uses telehealth consultations, medication tracking, and nutritional assessments to enhance care access and monitor intervention outcomes.",[13,14,15],"Behavioral: Local intervention program","Behavioral: Referral Process","Behavioral: Telehealth Education & Digital Integration",{"label":17,"type":18,"description":19,"interventionNames":20},"Control","NO_INTERVENTION","Participants in the control group will undergo the same baseline and follow-up assessments as the intervention group. After evaluation, they will be informed of any abnormal findings and provided with recommendations for appropriate medical referrals based on standard care practices.\n\nHowever, no additional referral assistance, intervention programs, or follow-up services will be provided beyond the basic healthcare guidance currently available in the community.",null,[22,27,31],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":20},"BEHAVIORAL","Local intervention program","HI-HOPE Project introduces a three-phase intervention program Phase 1: \"Active Mind \\& Body\" (12 Weeks) Focus: Cognitive enhancement, depression relief, and music-based movement therapy.\n\nDelivery: Certified community instructors. Schedule: 1 session\u002Fweek, 2 hours per session (total 12 sessions). Supplementary Exercise: High-intensity training by professional coaches (1 session\u002Fweek, 1 hour per session).\n\nPhase 2: \"Complete Senior Wellness\" (12 Weeks) Focus: Comprehensive functional improvement covering all six ICOPE domains. Delivery: Certified community instructors. Schedule: 1 session\u002Fweek, 2 hours per session (total 12 sessions). Supplementary Exercise: High-intensity training by professional coaches (1 session\u002Fweek, 1 hour per session).\n\nPhase 3: \"Advanced Exercise Training\" (12 Weeks) Focus: Strengthening self-care abilities and increasing acceptance of medical interventions.\n\nDelivery: Professional exercise coaches. Schedule: 2 sessions\u002Fweek, 1 hour per session (total 24 sessions).",[9],{"type":23,"name":28,"description":29,"armGroupLabels":30,"otherNames":20},"Referral Process","Self-referral tracking (1-2 weeks): Participants able to visit referral sites independently will be followed up to confirm completion.\n\nBarrier assessment: If unable to attend, interviews will identify obstacles (e.g., transport, finances, willingness).\n\nTransportation support: Solutions include volunteer transport with fuel subsidies, local transport networks, and government-assisted group referrals.\n\nFinancial assistance: Eligibility for social welfare aid will be assessed, with support for applications.\n\nPersonal willingness \\& health literacy: Health education will address concerns about treatment or social stigma.\n\nTelehealth consultations: Remote specialist consultations will be provided if in-person visits are not possible.\n\nHospital-based referral support: Group hospital visits will be arranged for those with referral difficulties.\n\nMonthly tracking: Referral completion rates and outcomes will be monitored (e.g., treatments, assistive devices, social services).",[9],{"type":23,"name":32,"description":33,"armGroupLabels":34,"otherNames":20},"Telehealth Education & Digital Integration","Live-streamed health education across multiple community sites.\n\nDigital health platforms for real-time intervention monitoring and professional feedback:\n\nPolypharmacy management via medication usage tracking and pharmacist analysis. Nutritional assessment with dietitian recommendations. Health consultations provided remotely by specialists based on screening results.",[9],[36],{"name":37,"role":38,"phone":39,"phoneExt":20,"email":40},"Kai-Chieh Chang, MD","CONTACT","+886930220332","b94401022@ntu.edu.tw",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","National Taiwan University Clinical Trial Center","Superintendent, National Taiwan Univerisity Hospital Yunlin Branch",[46,48],{"name":47,"class":6},"National Taiwan University Hospital, Yun-Lin Branch",{"name":49,"class":6},"National Health Research Institutes, Taiwan","100583907","holistic-integration-for-healthy-longevity-and-aging-in-place-100583907",false,"NCT06882434","Holistic Integration for Healthy Longevity and Aging in Place","Holistic Integration for Healthy Longevity and Aging in Place - Establishing Full-spectrum Community-based Care System for Older People to Maintain Wellbeing Pursuing Abilities","HIHOPE","Inclusion Criteria:\n\n* Age ≥55 years (includes older adults and pre-elderly individuals).\n* No severe functional disability (must be able to walk independently, use assistive devices, or operate a wheelchair independently).\n* No severe cognitive impairment (must be able to respond appropriately to verbal questions).\n\nExclusion Criteria:\n\n* Irregular community participation (less than once per week in the target community).\n* Mild dementia or greater (assessed during screening). If identified, family members will be notified, and they retain the right to withdraw the participant unconditionally.",true,"ALL","55 Years",{"count":62,"type":63},600,"ESTIMATED","INTERVENTIONAL",[66],"NA","Background:\n\nTaiwan is experiencing rapid population aging, with a growing prevalence of chronic diseases and functional impairments among older adults. Existing Integrated Care for Older People (ICOPE) programs focus primarily on screening but lack sufficient follow-up and intervention. In response, the HI-HOPE Project was developed to establish a community-based, multidisciplinary intervention model to enhance intrinsic capacity and promote healthy aging in rural elderly populations.\n\nSurvey and Screening:\n\nThe study will be conducted in 30 community centers across Yunlin County, targeting older adults aged ≥55 years. Participants will undergo biannual screenings over two years, assessing cognitive function, depression, mobility, vitality (nutrition), hearing, vision, osteoporosis, polypharmacy, urological health, and social participation \\& welfare.\n\nIntervention:\n\nParticipants will be randomly assigned to either:\n\nHI-HOPE Integrated Care Group:\n\nOn-Site Community Interventions: Exercise training, mindfulness, social activities, oral and swallowing rehabilitation, hearing and vision training.\n\nTelehealth \\& Remote Education: Digital health monitoring, remote consultations, and health education.\n\nReferral Services: Access to specialized medical care, transportation assistance, and follow-up support.\n\nControl Group: Standard community care services without additional structured interventions.\n\nOutcome Measures:\n\nPrimary outcomes include changes in intrinsic capacity of functional health metrics, including abnormalities of I-COPE components (mobility, cognitive status, depression, hearing, vision, vitality) . Secondary outcomes assess quality of life, activities of daily living, hospitalization, emergency visits, falls, and mortality rates over two years.\n\nSignificance:\n\nThis project integrates digital health technologies, interdisciplinary care, and community-based interventions to improve elderly health outcomes. The findings will guide the future scalability of integrated aging care models in Taiwan and beyond.",[69,70,71,72,73,74,75,76,77,78],"Cognitive Decline","Sarcopenia","Depression Disorders","Nutrition Disorder","Swallowing Difficulties","Hearing Disorder","Visual Disorder","Osteoporosis","Urologic Disorders","Polypharmacy",[56,80,81,82,83,84,85,86,87,88,89,90,91],"I-COPE","dementia","depression","dysphagia","nutrition","sarcopenia","frailty","hearing disorder","visual disorder","osteoporosis","urologic disorder","polypharmacy","NOT_YET_RECRUITING","2025-03-20",{"date":95,"type":96},"2025-03-25","ACTUAL",{"date":98,"type":63},"2025-03-15",{"date":100,"type":63},"2028-12-31",{"name":5,"class":6}]