[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100529959":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":22,"responsibleParty":41,"collaborators":7,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":7,"enrollmentInfo":52,"targetDuration":55,"studyType":56,"phases":7,"briefSummary":57,"conditions":58,"keywords":7,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Universität des Saarlandes","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","DKK-3","DKK-3-Urine measurement",[14],{"name":15,"affiliation":5,"role":16},"Stefan Neuhaus, MD","PRINCIPAL_INVESTIGATOR",[18],{"name":15,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","+4968411615041","stefan.neuhaus@uks.eu",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Universitätsklinikum des Saarlandes","RECRUITING","Homburg","Saarland","66421","Germany","DE",{"type":32,"coordinates":33},"Point",[34,35],7.33867,49.32637,{"lat":35,"lon":34},[38],{"name":15,"role":19,"phone":39,"phoneExt":40,"email":21},"+49684116","15041",{"type":42,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100529959","homburg-renal-evaluation-study-on-the-clinical-utility-of-early-aki-diagnosis-100529959",false,"NCT06180551","Homburg Renal Evaluation Study on the Clinical Utility of Early AKI Diagnosis","RESCUE-AKI","Inclusion Criteria:\n\n* Patients treated on the intensive care units of Saarland University Hospital.\n\nExclusion Criteria:\n\n* Patients on renal replacement treatment before admission to the intensive care unit.\n* Patients with chronic kidney disease stage CKD G3b or below.\n* Known kidney disease.\n* Kidney transplantation.\n* Intoxications leading to dialysis treatment.\n* Participation in other clinical trials.","ALL","18 Years",{"count":53,"type":54},1000,"ESTIMATED","2 Years","OBSERVATIONAL","Critically ill patients are at risk of developing a sudden decrease of kidney function which may be detected by a decrease in urine output or is diagnosed on the basis of blood tests for substances normally eliminated by the kidney, primarily creatinine.\n\nBecause it takes about 24 hours for the creatinine level to rise, even if both kidneys have ceased to function, better markers are needed.\n\nThis trial is investigating if the marker urinary dickkopf-3 (uDKK3) allows an early prediction of a sudden decrease of kidney function.",[59],"Acute Kidney Injury","2023-12-12",{"date":62,"type":63},"2023-12-22","ACTUAL",{"date":65,"type":63},"2023-12-01",{"date":67,"type":54},"2027-06",{"name":5,"class":6},1]