[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610290":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":17,"centralContacts":23,"locations":33,"responsibleParty":79,"collaborators":83,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":89,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":17,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":36,"whyStopped":17,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Shady Grove Fertility Reproductive Science Center","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Holiday","Patients will undergo a 2 month drug holiday (pause) with combined hormonal contraceptives prior to planned oocyte cryopreservation",[12],"Other: OCP pause",{"label":14,"type":15,"description":16,"interventionNames":17},"Immediate Start","NO_INTERVENTION","Patients will immediately begin planned oocyte cryopreservation after discontinuation of prolonged combined hormonal contraceptive",null,[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":17},"OCP pause","Subjects in the study arm will be asked to discontinue combined hormonal contraceptives (CHC) for 2 months prior to planned oocyte cryopreservation",[9],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":17,"email":28},"Tasha Newsome, Clinical Research Supervisor","CONTACT","301-545-1289","Tasha.Newsome@sgfertility.com",{"name":30,"role":26,"phone":31,"phoneExt":17,"email":32},"Seth J Barishansky, MD","475-267-9469","HolidayStudy@USFertility.com",[34,50,65],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Yale Fertility Center","RECRUITING","Orange","Connecticut","06477","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-73.02566,41.27843,{"lat":46,"lon":45},[49],{"name":30,"role":26,"phone":31,"phoneExt":17,"email":32},{"facility":51,"status":36,"city":52,"state":53,"zip":54,"country":40,"countryCode":41,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Shady Grove Fertility Rockville","Rockville","Maryland","20850",{"type":43,"coordinates":56},[57,58],-77.15276,39.084,{"lat":58,"lon":57},[61,63],{"name":62,"role":26,"phone":27,"phoneExt":17,"email":28},"Tasha Newsome, 301-545-1289",{"name":64,"role":26,"phone":17,"phoneExt":17,"email":32},"Amalia Namath, MD",{"facility":66,"status":67,"city":68,"state":68,"zip":69,"country":40,"countryCode":41,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Reproductive Medicine Associates of New York","NOT_YET_RECRUITING","New York","10022",{"type":43,"coordinates":71},[72,73],-74.00597,40.71427,{"lat":73,"lon":72},[76],{"name":77,"role":26,"phone":78,"phoneExt":17,"email":32},"Miriam Andrusier, MD","212-756-5777 ext 88270",{"type":80,"investigatorFullName":81,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Kate Devine","Medical Director and Chief Research Officer, USFertility",[84],{"name":85,"class":86},"EMD Serono","INDUSTRY","100610290","hormonal-optimization-late-vs-immediate-start-after-discontinuation-of-oral-contraceptives-in-assisted-reproductive-technology-holiday-100610290",false,"NCT07225660","Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)","A Randomized Blinded Controlled Trial Assessing Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)","HOLIDAY","Inclusion Criteria:\n\n1. Ovary-bearing individuals 18 to 40 years of age.\n2. BMI \\\u003C 40 kg\u002Fm2\n3. Non-smoker for at least 3 months prior to study enrollment.\n\nExclusion Criteria:\n\n1. BMI greater than or equal to 40 kg\u002Fm2\n2. Current Smoker\n3. Any contraindications to ovarian stimulation or outpatient egg retrieval under anesthesia","FEMALE","18 Years","40 Years",{"count":99,"type":100},394,"ESTIMATED","INTERVENTIONAL",[103],"NA","HOLIDAY is a two-arm, parallel-group, multi-center, randomized trial in which subjects undergoing planned oocyte cryopreservation will be randomized to receive either a 2-month pause of Combined Hormonal Contraceptives (CHC) or immediate start (without a pause).",[106],"Fertility Preservation",[108],"planned oocyte cryopreservation","2026-02-26",{"date":111,"type":112},"2026-03-02","ACTUAL",{"date":114,"type":112},"2026-02-25",{"date":116,"type":100},"2027-07-01",{"name":5,"class":6},3]