[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590845":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":76,"collaborators":26,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":26,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Duke University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of Care","PLACEBO_COMPARATOR","The control arm will receive standard counseling regarding post operative HRT by their gynecologic oncologist during their visit, as well as standardized written education in their after-visit summary.",[13],"Behavioral: SOC Arm",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental","EXPERIMENTAL","The experimental arm will receive standard verbal counseling and written education plus the video-based educational aid describing the risks and benefits of HRT.",[19],"Behavioral: Experimental Arm",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Experimental Arm","Participants will be randomized to SOC plus the video.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"SOC Arm","Participants will be randomized to SOC counseling.",[9],[32],{"name":33,"affiliation":5,"role":34},"Laura Havrilesky","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Amelia Scott","CONTACT","(919) 613-4584","amelia.lorenzo@duke.edu",[42,62],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"UNC Chapel Hill Health System","RECRUITING","Chapel Hill","North Carolina","27514","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-79.05584,35.9132,{"lat":54,"lon":53},[57,61],{"name":58,"role":38,"phone":59,"phoneExt":26,"email":60},"Katherine Tucker, MD","919-966-2131","Katherine.Tucker2@unchealth.unc.edu",{"name":58,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":63,"status":44,"city":64,"state":46,"zip":65,"country":48,"countryCode":49,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Duke University Health System","Durham","27710",{"type":51,"coordinates":67},[68,69],-78.89862,35.99403,{"lat":69,"lon":68},[72,74],{"name":37,"role":38,"phone":73,"phoneExt":26,"email":40},"919-613-4584",{"name":75,"role":34,"phone":26,"phoneExt":26,"email":26},"Laura Havrilesky, MD",{"type":77,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100590845","hormone-replacement-therapy-after-risk-reducing-salpingo-oophorectomy-100590845",false,"NCT06972719","Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy","Patient Centered Education About Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy: a Pilot Randomized Controlled Trial","BRCA HRT Pilot","Inclusion Criteria:\n\n* BRCA1 or BRCA2 germline mutation\n* scheduled for a risk-reducing salpingo-oophorectomy (RRSO) by Duke Gynecologic Oncologist\n* premenopausal\n\nExclusion Criteria:\n\n* personal history of cancer\n* postmenopausal\n* \\>50 years old\n* unable to provide informed consent in English","FEMALE","19 Years","50 Years",{"count":90,"type":91},50,"ESTIMATED","INTERVENTIONAL",[94],"NA","The goal of this study is to develop an educational aid about hormone replacement therapy that physicians can share with patients as part of their pre-surgical counseling for a risk-reducing salpingo-oophorectomy (RRSO).",[97,98],"BRCA1 Mutation","BRCA2 Mutation","2026-03-25",{"date":101,"type":102},"2026-03-27","ACTUAL",{"date":104,"type":102},"2025-09-30",{"date":106,"type":91},"2026-12-31",{"name":5,"class":6},2]