[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563063":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":48,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Imperial College London","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Volunteers taking part in study",null,[12],"Diagnostic Test: Breath test",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DIAGNOSTIC_TEST","Breath test","Participants will perform breath testing in Primary care followed by Secondary care on Day 1. At each location, participants will be asked to perform three breath tests (15 minutes apart). The environmental air will also be sampled.\n\nThis entire process will be repeated in the reverse order (i.e. breath testing in Secondary care followed by Primary care on Day 2).\n\nParticipants will be asked to maintain a clear fluid diet for a minimum of six hours prior to breath collection on both Day 1 and Day 2 of sampling.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Michael Fadel, BSc MBBS MRCS","CONTACT","+44 (0)20 7594 3396","m.fadel@imperial.ac.uk",[26,38],{"facility":5,"status":27,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"NOT_YET_RECRUITING","London","W12 0NN","United Kingdom","UK",{"type":33,"coordinates":34},"Point",[35,36],-0.12574,51.50853,{"lat":36,"lon":35},{"facility":5,"status":39,"city":28,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":40,"geoPoint":42,"contacts":43},"RECRUITING",{"type":33,"coordinates":41},[35,36],{"lat":36,"lon":35},[44],{"name":45,"role":22,"phone":46,"phoneExt":10,"email":47},"Mohamed Abulazayem","+44 (0)020 7589 5111","m.abulazayem@imperial.ac.uk",{"type":49,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100563063","hospital-versus-primary-care-breath-test-environment-hope-study-100563063",false,"NCT06611293","HOspital Versus Primary Care Breath Test Environment (HOPE) Study","HOPE","Inclusion Criteria:\n\nParticipants will be:\n\n* Aged ≥ 18 years old\n* Willing and able to provide informed consent to take part in study.\n\nExclusion Criteria:\n\n* Pregnant women will be excluded from this study. With the exception of pregnant women, there are no additional strict exclusion criteria as individuals will act as their own control.",true,"ALL","18 Years",{"count":61,"type":62},80,"ESTIMATED","OBSERVATIONAL","Through the HOPE study, the intention would be to determine whether exhaled breath volatile organic compound (VOC) profiles in Primary care differ from Secondary care. The intention would also be to assess intra-subject variability of participants. This would allow us to determine if the results of breath samples are reproducible regardless of whether they are performed in a Primary or Secondary care environment. This would support the clinical translation of breath research outcomes from studies performed in Secondary care, despite the breath test being intended for use in Primary care.\n\nThe chief investigator of the HOPE study is Professor George Hanna (Head of Department of Surgery and Cancer, and Professor of Surgical Sciences at Imperial College London).",[66],"Breath Test","2025-04-30",{"date":69,"type":70},"2025-05-01","ACTUAL",{"date":72,"type":70},"2025-02-05",{"date":74,"type":62},"2026-10",{"name":5,"class":6},2]