[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604667":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":13,"centralContacts":18,"locations":28,"responsibleParty":42,"collaborators":10,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":10,"maxAge":10,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":64,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Beijing Tsinghua Chang Gung Hospital","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"This group included BD patients",null,{"label":12,"type":10,"description":10,"interventionNames":10},"This group included healthy control",[14],{"name":15,"affiliation":16,"role":17},"Shuo Jin, Principal Investigator","Beijing Tsinghua Changgeng Hospital","PRINCIPAL_INVESTIGATOR",[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Siqiao Shan","CONTACT","+86 13683156996","dsqs01567@btch.edu.cn",{"name":25,"role":21,"phone":10,"phoneExt":26,"email":27},"Shuo Jin","+86 1861117271","jsa01263@btch.edu.cn",[29],{"facility":30,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":10},"Beijing Tsinghua Changgung Hospital","Beijing","Beijing Municipality","102218","China","CN",{"type":37,"coordinates":38},"Point",[39,40],116.39723,39.9075,{"lat":40,"lon":39},{"type":17,"investigatorFullName":25,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Associate Chief Physician","100604667","host-microbe-interactions-in-biliary-dilatation-100604667",false,"NCT07152496","Host-Microbe Interactions in Biliary Dilatation","Integrated Transcriptome-Microbiome Profiling Reveals Host-Microbe Crosstalk in Biliary Dilatation","Inclusion Criteria:\n\nPatients who have been definitively diagnosed with biliary dilatation and are scheduled for surgical resection (Disease group) Healthy donor bile duct tissues discarded during organ transplantation procedures as part of routine surgical preparation (Control group)\n\nExclusion Criteria:\n\nPatients with severe systemic diseases that may affect study outcomes (Disease group) Insufficient tissue sample quality or quantity (Disease group) Unavailable or inadequate donor bile duct tissue samples (Control group)",true,"ALL",{"count":54,"type":55},400,"ESTIMATED","OBSERVATIONAL","This study is an observational cohort study aimed at continuously enrolling patients with biliary dilatation and healthy controls. It will collect bile duct tissue samples and clinical data from participants across all age groups to establish a comprehensive cohort for biliary dilatation research. Based on this cohort, the study seeks to investigate the molecular mechanisms underlying biliary dilatation development and progression, explore the role of host-microbiome interactions in disease processes, and identify biomarkers associated with complications and malignancy risk, to establish evidence-based strategies for improved diagnosis and treatment of biliary dilatation.",[59],"Choledochal Cyst",[61,62,63],"molecular mechanism","Biliary Dilatation","microbiome","NOT_YET_RECRUITING","2025-12-07",{"date":67,"type":68},"2025-12-09","ACTUAL",{"date":70,"type":55},"2025-12-15",{"date":72,"type":55},"2026-07-01",{"name":5,"class":6},1]