[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588237":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":65,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":25,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":25,"enrollmentInfo":80,"targetDuration":25,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":55,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of Aarhus","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate Transfusion Strategy","ACTIVE_COMPARATOR","Vital parameters, delirium screening, and blood samples are collected three times a day. If the hemoglobin level falls below the predefined threshold, red blood cell transfusion is administered without delay (within 4 hours).",[13],"Other: Blood Transfusion",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Care with Delayed Hemoglobin analysis","PLACEBO_COMPARATOR","The patients recieve standard care. To maintain patient blinding vital parameters, delirium screening, and blood samples are collected three times a day, just as in the intervention arm, however, hemoglobin analysis is delayed to avoid influencing transfusion decisions.",[19],"Other: Standard care",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Blood Transfusion","Blood transfusion is given without delay (within 4 hours) in case of hemoglobin below our threshold.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard care","These patients recieve our standard care including blood transfusion as usual. Vital parameters and delirium screening are collected three times a day.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Johanne Bech, MD","CONTACT","+4578431286","jobech@clin.au.dk",[37,53],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Aarhus University Hospital","NOT_YET_RECRUITING","Aarhus","Central Jutland","8200","Denmark","DK",{"type":46,"coordinates":47},"Point",[48,49],10.21076,56.15674,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"facility":54,"status":55,"city":56,"state":41,"zip":57,"country":43,"countryCode":44,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Gødstrup Hospital, Department of internal medicine","RECRUITING","Herning","7400",{"type":46,"coordinates":59},[60,61],8.97662,56.13615,{"lat":61,"lon":60},[64],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":66,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[68,70],{"name":69,"class":6},"Gødstrup Hospital",{"name":38,"class":6},"100588237","how-bleeding-affects-delirium-in-older-patients-with-hip-fractures-the-improve-hip-study-100588237",false,"NCT06938789","How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study","The Impact of Bleeding on Delirium Outcomes in Older Patients With Hip Fractures: A Single-Blind, Randomized Controlled Trial - The IMPROVE-HIP Study","Inclusion Criteria:\n\n* Hip fracture\n\nExclusion Criteria:\n\n* Pathological hip fracture\n* Periprosthtic fracture\n* Unable to speak or understand Danish\n* Does not wish to recieve blood transfusion\n* If the investigator finds the patient unable to cooperate to the study (e.g. in case of severe dementia and externalizing behaviour)","ALL","75 Years",{"count":81,"type":82},198,"ESTIMATED","INTERVENTIONAL",[85],"NA","The goal of this clinical trial is to investigate whether early detection of bleeding and prompt blood transfusions can help prevent delirium in patients aged 75 and older who are admitted to the hospital with hip fractures. The main question the trial aims to answer is:\n\nDo patients aged 75 and older with hip fractures benefit from earlier treatment of anemia (low blood count) to reduce the risk of delirium?\n\nResearchers will compare early diagnosis and treatment of bleeding with standard care to determine if it helps lower the risk of developing delirium.\n\nParticipants will:\n\nUndergo blood tests, have their vital signs monitored, and be screened for delirium three times a day for the first 48 hours after surgery.\n\nReceive blood transfusions promptly if their hemoglobin levels fall below a specified threshold.\n\nAttend a follow-up visit at 30 days to assess cognitive function and overall quality of life.\n\nAttend another follow-up at 90 days to evaluate hospital readmissions and survival.",[88,89,90],"Bleeding","Hip Fracture","Delirium - Postoperative",[92,93,94],"Hip fracture","Delirium","Blood transfusion","2026-05-19",{"date":97,"type":98},"2026-05-22","ACTUAL",{"date":100,"type":98},"2025-04-24",{"date":102,"type":82},"2027-06-01",{"name":5,"class":6},2]