[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587267":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":17,"centralContacts":22,"locations":32,"responsibleParty":52,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":10,"maxAge":10,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Guangzhou Women and Children's Medical Center","OTHER",[8],{"label":9,"type":10,"description":9,"interventionNames":11},"No treatment",null,[12],"Other: No intervention",[14],{"type":6,"name":15,"description":15,"armGroupLabels":16,"otherNames":10},"No intervention",[9],[18],{"name":19,"affiliation":20,"role":21},"Xiu Qiu, PhD","Study Principal Investigator Guangzhou Women and Children's Medical Center, China","PRINCIPAL_INVESTIGATOR",[23,28],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Xiu Qiu,, PhD","CONTACT","0086 20 38367160","qxiu0161@163.com",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":31},"Jianrong He, PhD","0086 20 38367159","jianrong.he@bigcs.org",[33],{"facility":34,"status":35,"city":36,"state":10,"zip":10,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Guangzhou Women and Children's Medical Center, China","RECRUITING","Guangzhou","China","CN",{"type":40,"coordinates":41},"Point",[42,43],113.25,23.11667,{"lat":43,"lon":42},[46,50],{"name":47,"role":25,"phone":48,"phoneExt":10,"email":49},"Xiu Qiu, MD,PhD","86-020-38367160","xiu.qiu@bigcs.org",{"name":51,"role":25,"phone":48,"phoneExt":10,"email":31},"Jian-Rong He, MD, PhD",{"type":21,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Xiu Qiu","The division of the born in Guangzhou cohort study","100587267","human-genes-and-microbiota-in-early-life-100587267",false,"NCT06926166","Human Genes and Microbiota in Early Life","Human Genes and Microbiota in Early Life (HuGME)","HuGME","Inclusion Criteria:\n\nPregnant women with \\\u003C 20 weeks of gestation Pregnant women intended to eventually deliver in Guangzhou Women and Children's medical center Permanent residengts of families intended to remain in Guangzhou with their child for ≥3 years\n\nExclusion Criteria:\n\nRefuses to have blood and stool samples stored at Born in Guangzhou cohort study Biobank.",true,"ALL",{"count":66,"type":67},20000,"ESTIMATED","OBSERVATIONAL","The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life and their interaction with the host on maternal-offspring health consequences in later life in the born in Guangzhou cohort study in China. Identification of the effect of microbiota in early life, as well as environmental factors and microbe-host interaction, will lead to a better understanding of disease pathogenesis and provide a foundation for targeted mechanistic investigation into the consequences of microbial-host crosstalk for long-term health. It also can result in new strategies to predict and prevent diseases in later life.",[71,72,73,74,75,76,77],"Host and Microbiome","Pregnancy Outcomes","Pregnancy Complications","Neurodevelopmental Disorders","Immune Development","Childhood Obesity","Type 2 Diabetes","2025-04-07",{"date":80,"type":81},"2025-04-13","ACTUAL",{"date":83,"type":81},"2019-04-01",{"date":85,"type":67},"2038-12-31",{"name":5,"class":6},1]