[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595524":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":21,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":21,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":21,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":39,"whyStopped":21,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Fujian Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hybrid Endoscopic Hemithyroidectomy + Same-Session Contralateral RFA","EXPERIMENTAL","Remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI central-neck dissection on the dominant lobe, immediately followed-under the same anesthesia-by ultrasound-guided radiofrequency ablation (17-G, 0.7 cm active tip, 40 W, moving-shot technique) of a ≤ 7 mm contralateral papillary thyroid microcarcinoma.",[13,14],"Procedure: Endoscopic Hemithyroidectomy with Central-Neck Dissection","Procedure: Ultrasound-Guided Radiofrequency Ablation of Contralateral Nodule",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"PROCEDURE","Endoscopic Hemithyroidectomy with Central-Neck Dissection","Gas-less axillo-breast approach (trans-axillary + peri-areolar), carbon-dioxide-free working space, removing dominant thyroid lobe plus level VI lymph nodes; intra-operative neuromonitoring used throughout.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Ultrasound-Guided Radiofrequency Ablation of Contralateral Nodule","17-gauge internally-cooled electrode, 0.7 cm active tip, power 40 W; moving-shot technique under real-time ultrasound until hyperechoic halo fully covers ≤ 7 mm papillary microcarcinoma ≥ 2 mm from posterior capsule; same anesthesia session as surgery.",[9],[27],{"name":28,"affiliation":29,"role":30},"Bo Wang MD, Principal Investigator","Fujian Medical University Union Hospital","PRINCIPAL_INVESTIGATOR",[32],{"name":33,"role":34,"phone":35,"phoneExt":21,"email":36},"Bo Wang Professor, MD","CONTACT","+13959123550","wangbo@fjmu.edu.cn",[38],{"facility":29,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Fuzhou","Fujian","350001","China","CN",{"type":46,"coordinates":47},"Point",[48,49],119.30611,26.06139,{"lat":49,"lon":48},[52,54],{"name":53,"role":34,"phone":35,"phoneExt":21,"email":36},"Bo Wang Porfessor, MD",{"name":28,"role":30,"phone":21,"phoneExt":21,"email":21},{"type":30,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Bo Wang,MD","Director, Head of Thyroid Surgery, Principal Investigator, Clinical Professor","100595524","hybrid-endoscopic-hemithyroidectomy-and-targeted-ablation-for-bilateral-papillary-thyroid-carcinoma-100595524",false,"NCT07033572","Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma","Inclusion Criteria:\n\n* Age 18-65 years.\n* Dominant-side PTC ≤1.5 cm suitable for endoscopic resection.\n* Contralateral nodule ≤7 mm located ≥2 mm from posterior capsule.\n* No radiologic lymph-node metastasis on contralateral side.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Extrathyroidal extension, gross nodal or distant metastasis.\n* Prior neck surgery, prior RFA\u002Fethanol injection, or neck irradiation.\n* Pregnancy or lactation.\n* Serious comorbidities precluding anesthesia or follow-up.","ALL","18 Years","65 Years",{"count":68,"type":69},60,"ESTIMATED","INTERVENTIONAL",[72],"NA","This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC). Eligible adults undergo remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI dissection on the dominant side, followed by ultrasound-guided radiofrequency ablation (RFA) of a ≤7 mm contralateral focus during the same anesthesia. Outcomes include structural-recurrence-free survival, endocrine-function preservation, safety, and quality of life over 24 months.",[75,76],"Thyroid Neoplasms","Carcinoma, Papillary",[78,79,80,81],"Hybrid endoscopic thyroidectomy","Radiofrequency ablation","Thyroid function preservation","Bilateral Thyroid Carcinoma","2025-07-01",{"date":84,"type":85},"2025-07-03","ACTUAL",{"date":87,"type":85},"2018-06-01",{"date":89,"type":69},"2028-06-30",{"name":5,"class":6},1]